Biphasic Insulin Aspart Given Thrice Daily is as Efficacious as a Basal-Bolus Insulin Regimen with Four Daily Injections

2006 ◽  
Vol 114 (09) ◽  
pp. 511-519 ◽  
Author(s):  
R. Ligthelm ◽  
U. Mouritzen ◽  
H. Lynggaard ◽  
M. Landin-Olsson ◽  
C. Fox ◽  
...  
2014 ◽  
Vol 8 (2) ◽  
pp. 111-117 ◽  
Author(s):  
Guillermo Dieuzeide ◽  
Lee-Ming Chuang ◽  
Abdulrahman Almaghamsi ◽  
Alexey Zilov ◽  
Jian-Wen Chen ◽  
...  

2021 ◽  
Vol 24 (3) ◽  
pp. 196
Author(s):  
Irace, C.

The basal-bolus insulin regimen in the management of diabetes is essential to achieve the recommended glycosylated hemoglobin (HbA1c) to reduce the incidence or the progression of chronic complications. HbA1c is influenced by either fasting plasma glucose and post-prandial hyperglycemia. Faster Aspart is an insulin Aspart with two additional excipients, L-arginine and niacinamide, which provide a faster subcutaneous absorption, the earlier onset of appearance, and consequently the optimization of post-prandial glucose control. Faster Aspart has been widely investigated in the ‘‘onset’’ clinical trials, which show better post-prandial glycemic excursions and noninferiority compared to insulin Aspart with HbA1c reduction. Clinical evidence demonstrates that faster Aspart is a therapeutic option able to provide clinical benefits over the current rapid-acting insulin analogs in terms of improved meal-related glycaemic control in subjects with diabetes. KEY WORDS post-prandial hyperglycemia; cardiovascular disease; insulin treatment; faster-acting insulin; faster aspart.


2013 ◽  
Vol 4 (2) ◽  
pp. 309-319 ◽  
Author(s):  
Jihad Haddad ◽  
Mohsen Khoshniatnikoo ◽  
Youcef Benabbas ◽  
Serdar Guler ◽  
Vinay Prusty ◽  
...  

2004 ◽  
Vol 66 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Mark L. Warren ◽  
Martin J. Conway ◽  
Leslie J. Klaff ◽  
Julio Rosenstock ◽  
Elsie Allen

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