scholarly journals Time-resolved energy transfer in DNA sequence detection using water-soluble conjugated polymers: The role of electrostatic and hydrophobic interactions

2004 ◽  
Vol 101 (32) ◽  
pp. 11634-11639 ◽  
Author(s):  
Q.-H. Xu ◽  
B. S. Gaylord ◽  
S. Wang ◽  
G. C. Bazan ◽  
D. Moses ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Conjugated Polymers ◽  
Dna Sequence ◽  
Hydrophobic Interactions ◽  
Water Soluble ◽  
Sequence Detection ◽  
Time Resolved ◽  
Electrostatic And Hydrophobic Interactions ◽  
Dna Sequence Detection

scholarly journals A New FRET-Based Sensitive DNA Sensor for Medical Diagnostics using PNA Probe and Water-Soluble Blue Light Emitting Polymer

2008 ◽  
Vol 2008 ◽  
pp. 1-6 ◽  
Author(s):  
Nidhi Mathur ◽  
Anamika Aneja ◽  
P. K. Bhatnagar ◽  
P. C. Mathur
Keyword(s):  
Dna Sequence ◽  
Low Cost ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Medical Diagnostics ◽  
Water Soluble ◽  
Complementary Sequence ◽  
Sequence Detection ◽  
Light Emitting ◽  
Dna Sequence Detection

A reliable, fast, and low-cost biosensor for medical diagnostics using DNA sequence detection has been developed and tested for the detection of the bacterium “Bacillus anthracis.” In this sensor, Poly [9,9-di (6,6′- N,N′trimethylammonium) hexylfluorenyl-2, 7-diyl)-alt-co- (1,4-phenylene)] dibromide salt (PFP) has been taken as cationic conjugated polymer (CCP) and PNA attached with fluorescein dye (PNAC∗) as a probe. The basic principle of this sensor is that when aPNAC∗probe is hybridized with a single strand DNA (ssDNA) having complementary sequence, Forster resonance energy transfer (FRET) may take place from PFP to thePNAC∗/DNA complex. If the FRET is efficient, the photoluminescence from the PFP will be highly quenched and that fromPNAC∗will be enhanced. On the other hand, if the DNA sequence is noncomplementary to PNA, FRET will not occur.

Templated Metal Catalysis for Single Nucleotide Specific DNA Sequence Detection

2005 ◽  
Vol 127 (21) ◽  
pp. 7849-7856 ◽  
Author(s):  
Iris Boll ◽  
Roland Krämer ◽  
Jens Brunner ◽  
Andriy Mokhir
Keyword(s):  
Dna Sequence ◽  
Single Nucleotide ◽  
Sequence Detection ◽  
Metal Catalysis ◽  
Dna Sequence Detection

Excitation energy transfer in a cationic water-soluble conjugated co-polymer studied by time resolved anisotropy and fluorescence dynamics

2006 ◽  
Vol 421 (1-3) ◽  
pp. 205-209 ◽  
Author(s):  
D. Anestopoulos ◽  
M. Fakis ◽  
P. Persephonis ◽  
V. Giannetas ◽  
J. Mikroyannidis
Keyword(s):  
Energy Transfer ◽  
Excitation Energy ◽  
Excitation Energy Transfer ◽  
Water Soluble ◽  
Time Resolved

Ultrasensitive DNA sequence detection using nanoscale ZnO sensor arrays

2006 ◽  
Vol 17 (12) ◽  
pp. 2875-2881 ◽  
Author(s):  
Nitin Kumar ◽  
Adam Dorfman ◽  
Jong-in Hahm
Keyword(s):  
Dna Sequence ◽  
Sensor Arrays ◽  
Sequence Detection ◽  
Dna Sequence Detection
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