Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0905039107 ◽

2010 ◽

Vol 107 (23) ◽

pp. 10620-10625 ◽

Author(s):

I. K. Jang ◽

J. Zhang ◽

Y. J. Chiang ◽

H. K. Kole ◽

D. G. Cronshaw ◽

...

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Antigen Receptor ◽

Thymic Selection ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

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A Comparison of the Interaction of Shc and the Tyrosine Kinase ZAP-70 with the T Cell Antigen Receptor ζ Chain Tyrosine-based Activation Motif

Journal of Biological Chemistry ◽

10.1074/jbc.270.23.13981 ◽

1995 ◽

Vol 270 (23) ◽

pp. 13981-13986 ◽

Author(s):

Narin Osman ◽

Susan C. Lucas ◽

Helen Turner ◽

Doreen Cantrell

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Activation Motif

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Prolactin Stimulates Phosphorylation of the Human T-Cell Antigen Receptor Complex and ZAP-70 Tyrosine Kinase: A Potential Mechanism for Its Immunomodulation

Endocrinology ◽

10.1210/endo.139.2.5913 ◽

1998 ◽

Vol 139 (2) ◽

pp. 811-814 ◽

Author(s):

David W. Montgomery ◽

Joshua S. Krumenacker ◽

Arthur R. Buckley

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Antigen Receptor ◽

Receptor Complex ◽

Potential Mechanism ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Human T Cell ◽

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The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling.

The EMBO Journal ◽

10.1002/j.1460-2075.1996.tb01015.x ◽

1996 ◽

Vol 15 (22) ◽

pp. 6251-6261 ◽

Author(s):

D. H. Chu ◽

H. Spits ◽

J. F. Peyron ◽

R. B. Rowley ◽

J. B. Bolen ◽

...

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Protein Tyrosine Kinase ◽

Antigen Receptor ◽

Receptor Signaling ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling ◽

Syk Protein Tyrosine Kinase

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T cell antigen receptor activation pathways: The tyrosine kinase connection

Cell ◽

10.1016/0092-8674(91)90310-u ◽

1991 ◽

Vol 64 (5) ◽

pp. 875-878 ◽

Author(s):

Richard D. Klausner ◽

Lawrence E. Samelson

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Antigen Receptor ◽

Receptor Activation ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Activation Pathways

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Regulation of Protein Tyrosine Kinase Activation by the T-cell Antigen Receptor Chain

Cold Spring Harbor Symposia on Quantitative Biology ◽

10.1101/sqb.1992.057.01.014 ◽

1992 ◽

Vol 57 (0) ◽

pp. 107-116 ◽

Author(s):

A. Weiss ◽

A.C. Chan ◽

M. Iwashima ◽

D. Straus ◽

B.A. Irving

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Protein Tyrosine Kinase ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Kinase Activation ◽

Cell Antigen Receptor ◽

Protein Tyrosine ◽

Cell Antigen ◽

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Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.6.2037 ◽

1991 ◽

Vol 88 (6) ◽

pp. 2037-2041 ◽

Author(s):

G. A. Koretzky ◽

J. Picus ◽

T. Schultz ◽

A. Weiss

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Protein Tyrosine Kinase ◽

Tyrosine Phosphatase ◽

Interleukin 2 ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Protein Tyrosine ◽

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Dissection of T cell antigen receptor signaling using protein tyrosine kinase inhibitors

European Journal of Immunology ◽

10.1002/eji.1830240506 ◽

1994 ◽

Vol 24 (5) ◽

pp. 1046-1052 ◽

Author(s):

Cosima T. Baldari ◽

John L. Telford

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitors ◽

Protein Tyrosine Kinase ◽

Kinase Inhibitors ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

Antigen Receptor Signaling

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The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.88.20.9166 ◽

1991 ◽

Vol 88 (20) ◽

pp. 9166-9170 ◽

Author(s):

A. C. Chan ◽

B. A. Irving ◽

J. D. Fraser ◽

A. Weiss

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Antigen Receptor ◽

Receptor Stimulation ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Cell Antigen ◽

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Decreased signaling competence as a result of receptor overexpression: overexpression of CD4 reduces its ability to activate p56lck tyrosine kinase and to regulate T-cell antigen receptor expression in immature CD4+CD8+ thymocytes.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.22.10534 ◽

1993 ◽

Vol 90 (22) ◽

pp. 10534-10538 ◽

Author(s):

T. Nakayama ◽

D. L. Wiest ◽

K. M. Abraham ◽

T. I. Munitz ◽

R. M. Perlmutter ◽

...

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Antigen Receptor ◽

Receptor Expression ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

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In vivo association of Grb2 with pp116, a substrate of the T cell antigen receptor-activated protein tyrosine kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)31848-3 ◽

1994 ◽

Vol 269 (34) ◽

pp. 21608-21613

Author(s):

D.G. Motto ◽

S.E. Ross ◽

J.K. Jackman ◽

Q. Sun ◽

A.L. Olson ◽

...

Keyword(s):

T Cell ◽

Tyrosine Kinase ◽

Protein Tyrosine Kinase ◽

Antigen Receptor ◽

T Cell Antigen Receptor ◽

Cell Antigen Receptor ◽

Protein Tyrosine ◽

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