scholarly journals Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication.

1983 ◽  
Vol 80 (23) ◽  
pp. 7085-7089 ◽  
Author(s):  
R. Scheuermann ◽  
S. Tam ◽  
P. M. Burgers ◽  
C. Lu ◽  
H. Echols
Keyword(s):  
Escherichia Coli ◽  
Dna Replication ◽  
Gene Product ◽  
Dna Polymerase ◽  
Dna Polymerase Iii ◽  
Epsilon Subunit ◽  
Polymerase Iii

Polymerases and UV mutagenesis in Escherichia coli

Genome ◽  
1989 ◽  
Vol 31 (2) ◽  
pp. 572-577 ◽  
Author(s):  
B. A. Bridges ◽  
Helen Bates ◽  
Firdaus Sharif
Keyword(s):  
Escherichia Coli ◽  
Dna Repair ◽  
Nucleic Acid ◽  
Gene Product ◽  
Ultraviolet Light ◽  
Dna Polymerase ◽  
Dna Polymerase Iii ◽  
Uv Mutagenesis ◽  
Α Subunit ◽  
Polymerase Iii

Evidence for and against the involvement of the known nucleic acid polymerases in UV mutagenesis in Escherichia coli is reviewed. There is no evidence that rules out the participation of any of them when they are present but only one, the α subunit of DNA polymerase III holoenzyme (polC gene product) has been shown to be essential. It is argued that the PolC protein that functions in UV mutagenesis may not be immediately recognizable as one of the normal cellular polymerases or polymerase complexes.Key words: polymerases, ultraviolet light, mutagenesis, DNA repair, misincorporation.

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