scholarly journals Physical association of the human base-excision repair enzyme uracil DNA glycosylase with the 70,000-dalton catalytic subunit of DNA polymerase alpha.

1986 ◽  
Vol 83 (20) ◽  
pp. 7608-7612 ◽  
Author(s):  
G. Seal ◽  
M. A. Sirover
Keyword(s):  
Dna Polymerase ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Catalytic Subunit ◽  
Dna Glycosylase ◽  
Repair Enzyme ◽  
Uracil Dna Glycosylase ◽  
Dna Polymerase Alpha ◽  
Physical Association ◽  
Base Excision

scholarly journals Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54

2010 ◽  
Vol 91 (8) ◽  
pp. 2029-2033 ◽  
Author(s):  
Blair L. Strang ◽  
Donald M. Coen
Keyword(s):  
Dna Polymerase ◽  
Human Cytomegalovirus ◽  
Excision Repair ◽  
Catalytic Subunit ◽  
Dna Glycosylase ◽  
Viral Dna ◽  
Uracil Dna Glycosylase ◽  
Accessory Subunit ◽  
Base Excision

Interaction between human cytomegalovirus uracil DNA glycosylase (UL114) and the viral DNA polymerase accessory subunit (UL44) has been reported; however, no such association was found in proteomic studies of UL44-interacting proteins. Utilizing virus expressing FLAG-tagged UL114, nuclease-resistant association of UL44 and the DNA polymerase catalytic subunit UL54 with UL114 was observed by co-immunoprecipitation. Contrary to a previous report, we observed that UL114 was much less abundant than UL44. Interaction of UL114 with UL54, independent of the UL54 carboxyl terminus, but not with UL44 was detected in vitro. Our data are consistent with a direct UL114–UL54 interaction, and suggest that UL114 and UL54 act in concert during base excision repair of the viral genome.

scholarly journals Uracil-DNA Glycosylase in Base Excision Repair and Adaptive Immunity

2011 ◽  
Vol 286 (19) ◽  
pp. 16669-16680 ◽  
Author(s):  
Berit Doseth ◽  
Torkild Visnes ◽  
Anders Wallenius ◽  
Ida Ericsson ◽  
Antonio Sarno ◽  
...  
Keyword(s):  
Adaptive Immunity ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Glycosylase ◽  
Uracil Dna Glycosylase ◽  
Base Excision

scholarly journals The p53-Induced Oncogenic Phosphatase PPM1D Interacts with Uracil DNA Glycosylase and Suppresses Base Excision Repair

2004 ◽  
Vol 15 (4) ◽  
pp. 621-634 ◽  
Author(s):  
Xiongbin Lu ◽  
Dora Bocangel ◽  
Bonnie Nannenga ◽  
Hiroshi Yamaguchi ◽  
Ettore Appella ◽  
...  
Keyword(s):  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Glycosylase ◽  
Uracil Dna Glycosylase ◽  
Base Excision

scholarly journals Base-Excision Repair Activity of Uracil-DNA Glycosylase Monitored Using the Latch Zone of α-Hemolysin

2013 ◽  
Vol 135 (51) ◽  
pp. 19347-19353 ◽  
Author(s):  
Qian Jin ◽  
Aaron M. Fleming ◽  
Robert P. Johnson ◽  
Yun Ding ◽  
Cynthia J. Burrows ◽  
...  
Keyword(s):  
Base Excision Repair ◽  
Excision Repair ◽  
Dna Glycosylase ◽  
Uracil Dna Glycosylase ◽  
Repair Activity ◽  
Base Excision
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