Correction: Galactose at the Nonreducing Terminus of O-Linked Oligosaccharides of Mouse Egg Zona pellucida Glycoprotein ZP3 is Essential for the Glycoprotein's Sperm Receptor Activity

1988 ◽  
Vol 85 (24) ◽  
pp. 9600-9600 ◽  
Keyword(s):  
Zona Pellucida ◽  
Receptor Activity ◽  
Mouse Egg ◽  
Sperm Receptor

Identification of a secondary sperm receptor in the mouse egg zona pellucida: Role in maintenance of binding of acrosome-reacted sperm to eggs

1988 ◽  
Vol 128 (2) ◽  
pp. 376-385 ◽  
Author(s):  
Jeffrey D. Bleil ◽  
Jeffrey M. Greve ◽  
Paul M. Wassarman
Keyword(s):  
Zona Pellucida ◽  
Mouse Egg ◽  
Sperm Receptor

scholarly journals Porcine Zona Pellucida: Association of Sperm Receptor Activity with the α-Glycoprotein Component of the Mr = 55,000 Family1

1989 ◽  
Vol 41 (3) ◽  
pp. 523-532 ◽  
Author(s):  
Anthony G. Sacco ◽  
Edward C. Yurewicz ◽  
Marappa G. Subramanian ◽  
Paul D. Matzat
Keyword(s):  
Zona Pellucida ◽  
Receptor Activity ◽  
Sperm Receptor

scholarly journals O-linked oligosaccharides of mouse egg ZP3 account for its sperm receptor activity

Cell ◽  
1985 ◽  
Vol 41 (1) ◽  
pp. 313-324 ◽  
Author(s):  
Harvey M. Florman ◽  
Paul M. Wassarman
Keyword(s):  
Receptor Activity ◽  
Mouse Egg ◽  
Sperm Receptor

Profile of a mammalian sperm receptor

Development ◽  
1990 ◽  
Vol 108 (1) ◽  
pp. 1-17 ◽  
Author(s):  
P.M. Wassarman
Keyword(s):  
Gene Expression ◽  
Zona Pellucida ◽  
Specific Gene ◽  
Mammalian Development ◽  
Unique Nature ◽  
Mammalian Fertilization ◽  
Species Specific ◽  
Available Information ◽  
Mammalian Eggs ◽  
Sperm Receptor

Complementary molecules on the surface of eggs and sperm are responsible for species-specific interactions between gametes during fertilization in both plants and animals. In this essay, several aspects of current research on the mouse egg receptor for sperm, a zona pellucida glycoprotein called ZP3, are addressed. These include the structure, synthesis, and functions of the sperm receptor during oogenesis and fertilization in mice. Several conclusions are drawn from available information. These include (I) ZP3 is a member of a unique class of glycoproteins found exclusively in the extracellular coat (zona pellucida) of mammalian eggs. (II) ZP3 gene expression is an example of oocyte-specific and, therefore, sex-specific gene expression during mammalian development. (III) ZP3 is a structural glycoprotein involved in assembly of the egg extracellular coat during mammalian oogenesis. (IV) ZP3 is a sperm receptor involved in carbohydrate-mediated gamete recognition and adhesion during mammalian fertilization. (V) ZP3 is an inducer of sperm exocytosis (acrosome reaction) during mammalian fertilization. (VI) ZP3 participates in the secondary block to polyspermy following fertilization in mammals. (VII) The extracellular coat of other mammalian eggs contains a glycoprotein that is functionally analogous to mouse ZP3. The unique nature, highly restricted expression, and multiple roles of ZP3 during mammalian development make this glycoprotein a particularly attractive subject for investigation at both the cellular and molecular levels.

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