A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion.

J. L. Dul; Y. Argon

doi:10.1073/pnas.87.20.8135

A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.87.20.8135 ◽

1990 ◽

Vol 87 (20) ◽

pp. 8135-8139 ◽

Cited By ~ 53

Author(s):

J. L. Dul ◽

Y. Argon

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Light Chain ◽

Variable Region ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Immunoglobulin Secretion

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Secretion of a λ2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region

Cell ◽

10.1016/0092-8674(83)90336-7 ◽

1983 ◽

Vol 33 (1) ◽

pp. 77-83 ◽

Cited By ~ 53

Author(s):

Gillian E. Wu ◽

Nobumichi Hozumi ◽

Helios Murialdo

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Variable Region ◽

Single Amino Acid Substitution ◽

Single Amino Acid

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Differences in antigen-binding affinity caused by single amino acid substitution in the variable region of the heavy chain

Immunology and Cell Biology ◽

10.1038/icb.1993.28 ◽

1993 ◽

Vol 71 (4) ◽

pp. 239-247 ◽

Cited By ~ 6

Author(s):

JIM XIANG ◽

ZHINAN CHEN ◽

LOUIS T. J. DELBAERE ◽

ENWU LIU

Keyword(s):

Amino Acid ◽

Binding Affinity ◽

Amino Acid Substitution ◽

Heavy Chain ◽

Variable Region ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Antigen Binding

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Faculty Opinions recommendation of A single amino acid substitution in the movement protein enables the mechanical transmission of a geminivirus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737608820.793572784 ◽

2020 ◽

Author(s):

Vitaly Citovsky

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Movement Protein ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Mechanical Transmission

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A large compressibility change of protein induced by a single amino acid substitution

Protein Science ◽

10.1002/pro.5560050319 ◽

1996 ◽

Vol 5 (3) ◽

pp. 542-545 ◽

Cited By ~ 18

Author(s):

Kunihiko Gekko ◽

Youjiro Tamura ◽

Eiji Ohmae ◽

Hideyuki Hayashi ◽

Hiroyuki Kagamiyama ◽

...

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid

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A single amino acid substitution flanking the fourth calcium binding domain of alpha IIb prevents maturation of the alpha IIb beta 3 integrin complex.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)41800-x ◽

1994 ◽

Vol 269 (6) ◽

pp. 4450-4457

Author(s):

D.A. Wilcox ◽

J.L. Wautier ◽

D. Pidard ◽

P.J. Newman

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Calcium Binding ◽

Binding Domain ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Calcium Binding Domain

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A single amino acid substitution in the A subunit of Escherichia coli enterotoxin results in a loss of its toxic activity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)45736-5 ◽

1990 ◽

Vol 265 (36) ◽

pp. 22520-22525

Author(s):

T Tsuji ◽

T Inoue ◽

A Miyama ◽

K Okamoto ◽

T Honda ◽

...

Keyword(s):

Escherichia Coli ◽

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Toxic Activity ◽

A Subunit

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Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54166-1 ◽

1993 ◽

Vol 268 (1) ◽

pp. 410-415

Author(s):

K. Sakurada ◽

M. Masu ◽

S. Nakanishi

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Channel Blockers ◽

Aspartate Receptor

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A single amino acid substitution in the R2R3 conserved domain of the BrPAP1a transcription factor impairs anthocyanin production in turnip (Brassica rapa subsp. rapa)

Plant Physiology and Biochemistry ◽

10.1016/j.plaphy.2021.02.011 ◽

2021 ◽

Vol 162 ◽

pp. 124-136

Author(s):

Jianfei Yang ◽

Hyon Dok Song ◽

Yunzhu Chen ◽

Bowei Chen ◽

Minjun Kim ◽

...

Keyword(s):

Transcription Factor ◽

Amino Acid ◽

Brassica Rapa ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Conserved Domain ◽

Anthocyanin Production

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A single amino acid substitution in the Ω-like loop of E. coli PBP5 disrupts its ability to maintain cell shape and intrinsic beta-lactam resistance

Microbiology ◽

10.1099/mic.0.000052 ◽

2015 ◽

Vol 161 (4) ◽

pp. 895-902 ◽

Cited By ~ 11

Author(s):

Mouparna Dutta ◽

Debasish Kar ◽

Ankita Bansal ◽

Sandeep Chakraborty ◽

Anindya S. Ghosh

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Cell Shape ◽

Single Amino Acid Substitution ◽

Single Amino Acid ◽

Beta Lactam ◽

E Coli

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A single amino acid substitution in the H-2Kb molecule generates a defined allogeneic epitope

Molecular Immunology ◽

10.1016/0161-5890(93)90441-d ◽

1993 ◽

Vol 30 (18) ◽

pp. 1671-1677 ◽

Cited By ~ 2

Author(s):

Krishna V. Kesari ◽

Grada van Bleek ◽

Stanley G. Nathenson ◽

Jan Geliebter

Keyword(s):

Amino Acid ◽

Amino Acid Substitution ◽

Single Amino Acid Substitution ◽

Single Amino Acid

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