scholarly journals Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice.

1996 ◽  
Vol 93 (12) ◽  
pp. 6191-6196 ◽  
Author(s):  
S. M. Dymecki
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Transgenic Mice ◽  
Dna Recombination ◽  
Embryonic Stem ◽  
Site Specific ◽  
Flp Recombinase

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

genesis ◽  
2006 ◽  
Vol 44 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Caroline Beard ◽  
Konrad Hochedlinger ◽  
Kathrin Plath ◽  
Anton Wutz ◽  
Rudolf Jaenisch
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Transgenic Mice ◽  
Efficient Method ◽  
Embryonic Stem ◽  
Single Copy ◽  
Site Specific ◽  
Site Specific Integration

The Use of Genetically Modified Embryonic Stem Cells to Generate Transgenic Mice

2004 ◽  
Vol 40 (3) ◽  
pp. 235-238 ◽  
Author(s):  
M. V. Pryzhkova ◽  
I. R. Zakeeva ◽  
A. V. Kibardin ◽  
G. P. Georgiev ◽  
S. L. Kiselev
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Transgenic Mice ◽  
Genetically Modified ◽  
Embryonic Stem

Selective Disruption of Genes Transiently Induced in Differentiating Mouse Embryonic Stem Cells by Using Gene Trap Mutagenesis and Site-Specific Recombination

1998 ◽  
Vol 18 (10) ◽  
pp. 6164-6164
Author(s):  
Irmgard S. Thorey ◽  
Katrin Muth ◽  
Andreas P. Russ ◽  
Jürgen Otte ◽  
Armin Reffelmann ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Gene Trap ◽  
Site Specific ◽  
Site Specific Recombination

scholarly journals The length of homology required for gene targeting in embryonic stem cells

1991 ◽  
Vol 11 (11) ◽  
pp. 5586-5591 ◽  
Author(s):  
P Hasty ◽  
J Rivera-Pérez ◽  
A Bradley
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Homologous Recombination ◽  
Gene Targeting ◽  
Es Cells ◽  
Embryonic Stem ◽  
Critical Length ◽  
Gene Replacement ◽  
Site Specific ◽  
The Relationship

Homologous recombination has been used to introduce site-specific mutations into murine embryonic stem (ES) cells with both insertion and replacement vectors. In this study, we compared the frequency of gene targeting with various lengths of homology and found a dramatic increase in targeting with an increase in homology from 1.3 to 6.8 kb. We examined in detail the relationship between the length of homology and the gene-targeting frequency for replacement vectors and found that a critical length of homology is needed for targeting. Adding greater lengths of homology to this critical length has less of an effect on the targeting frequency. We also analyzed the lengths of homology necessary on both arms of the vector for gene replacement events and found that 472 bp of homology is used as efficiently as 1.2 kb in the formation and resolution of crossover junctions.

Androgenetic haploid embryonic stem cells produce live transgenic mice

Nature ◽  
2012 ◽  
Vol 490 (7420) ◽  
pp. 407-411 ◽  
Author(s):  
Wei Li ◽  
Ling Shuai ◽  
Haifeng Wan ◽  
Mingzhu Dong ◽  
Meng Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Transgenic Mice ◽  
Embryonic Stem ◽  
Androgenetic Haploid

scholarly journals  -Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

2008 ◽  
Vol 28 (16) ◽  
pp. 4250-4260 ◽  
Author(s):  
L. Crews ◽  
H. Mizuno ◽  
P. Desplats ◽  
E. Rockenstein ◽  
A. Adame ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Transgenic Mice ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Notch 1

Rapid selection of XO embryonic stem cells using Y chromosome-linked GFP transgenic mice

2014 ◽  
Vol 23 (5) ◽  
pp. 757-765 ◽  
Author(s):  
Satoshi Yamamoto ◽  
Yasumitsu Nagao ◽  
Kenji Kuroiwa ◽  
Yoji Hakamata ◽  
Masaru Ichida ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Transgenic Mice ◽  
Y Chromosome ◽  
Embryonic Stem ◽  
Selection Of
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