Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide

Endochondral Bone ◽

Related Peptide ◽

Targeted Expression ◽

Parathyroid Hormone Related Peptide ◽

Constitutively Active

Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.93.19.10240 ◽

1996 ◽

Vol 93 (19) ◽

pp. 10240-10245 ◽

Cited By ~ 326

Author(s):

E. C. Weir ◽

W. M. Philbrick ◽

M. Amling ◽

L. A. Neff ◽

R. Baron ◽

...

Keyword(s):

Parathyroid Hormone ◽

Bone Formation ◽

Endochondral Bone ◽

Related Peptide ◽

Thyroid Hormones Regulate Hypertrophic Chondrocyte Differentiation and Expression of Parathyroid Hormone-Related Peptide and Its Receptor During Endochondral Bone Formation

Journal of Bone and Mineral Research ◽

10.1359/jbmr.2000.15.12.2431 ◽

2000 ◽

Vol 15 (12) ◽

pp. 2431-2442 ◽

Cited By ~ 107

Author(s):

David A. Stevens ◽

Robert P. Hasserjian ◽

Helen Robson ◽

Thomas Siebler ◽

Stephen M. Shalet ◽

...

Keyword(s):

Parathyroid Hormone ◽

Bone Formation ◽

Thyroid Hormones ◽

Chondrocyte Differentiation ◽

Endochondral Bone ◽

Related Peptide ◽

Hypertrophic Chondrocyte ◽

Parathyroid hormone-related protein (PTHrP) as a regulating factor of endochondral bone formation

Oral Diseases ◽

10.1111/j.1601-0825.1997.tb00046.x ◽

2008 ◽

Vol 3 (4) ◽

pp. 229-231 ◽

Cited By ~ 9

Author(s):

N. Suda

Keyword(s):

Parathyroid Hormone ◽

Bone Formation ◽

Parathyroid Hormone Related Protein

Related Protein ◽

Endochondral Bone ◽

Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development.

Endocrinology ◽

10.1210/endo.137.11.8895385 ◽

1996 ◽

Vol 137 (11) ◽

pp. 5109-5118 ◽

Cited By ~ 154

Author(s):

K Lee ◽

B Lanske ◽

A C Karaplis ◽

J D Deeds ◽

H Kohno ◽

...

Keyword(s):

Parathyroid Hormone ◽

Bone Development ◽

Terminal Differentiation ◽

Endochondral Bone ◽

Related Peptide ◽

Dissociation of Bone Formation from Resorption during 2-Week Treatment with Human Parathyroid Hormone-Related Peptide-(1–36) in Humans: Potential as an Anabolic Therapy for Osteoporosis1

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem.83.8.5047 ◽

1998 ◽

Vol 83 (8) ◽

pp. 2786-2791

Author(s):

Horacio Plotkin ◽

Caren Gundberg ◽

Maryann Mitnick ◽

Andrew F. Stewart

Keyword(s):

Parathyroid Hormone ◽

Bone Formation ◽

Human Parathyroid Hormone ◽

Related Peptide ◽

Anabolic Therapy ◽

The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.95.22.13030 ◽

1998 ◽

Vol 95 (22) ◽

pp. 13030-13035 ◽

Cited By ~ 170

Author(s):

U.-i. Chung ◽

B. Lanske ◽

K. Lee ◽

E. Li ◽

H. Kronenberg

Keyword(s):

Parathyroid Hormone ◽

Bone Development ◽

Chondrocyte Differentiation ◽

Endochondral Bone ◽

Peptide Receptor ◽

Related Peptide ◽

Dissociation of Bone Formation from Resorption during 2-Week Treatment with Human Parathyroid Hormone-Related Peptide-(1-36) in Humans: Potential as an Anabolic Therapy for Osteoporosis

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.83.8.2786 ◽

1998 ◽

Vol 83 (8) ◽

pp. 2786-2791 ◽

Cited By ~ 12

Author(s):

H. Plotkin

Keyword(s):

Parathyroid Hormone ◽

Bone Formation ◽

Human Parathyroid Hormone ◽

Related Peptide ◽

Anabolic Therapy ◽

Identification of Determinants of Inverse Agonism in a Constitutively Active Parathyroid Hormone/Parathyroid Hormone-related Peptide Receptor by Photoaffinity Cross-linking and Mutational Analysis

Journal of Biological Chemistry ◽

10.1074/jbc.m106215200 ◽

2001 ◽

Vol 276 (46) ◽

pp. 42692-42699 ◽

Cited By ~ 29

Author(s):

Robert C. Gensure ◽

Percy H. Carter ◽

Brian D. Petroni ◽

Harald Jüppner ◽

Thomas J. Gardella

Keyword(s):

Parathyroid Hormone ◽

Mutational Analysis ◽

Cross Linking ◽

Peptide Receptor ◽

Related Peptide ◽

Inverse Agonism ◽

Parathyroid Hormone Related Peptide ◽

Constitutively Active

The C-terminal fragment of parathyroid hormone-related peptide promotes bone formation in diabetic mice with low-turnover osteopaenia

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2010.01155.x ◽

2011 ◽

Vol 162 (6) ◽

pp. 1424-1438 ◽

Cited By ~ 38

Author(s):

D Lozano ◽

L Fernández-de-Castro ◽

S Portal-Núñez ◽

A López-Herradón ◽

S Dapía ◽

...

Keyword(s):

Parathyroid Hormone ◽

Bone Formation ◽

Diabetic Mice ◽

Related Peptide ◽

Terminal Fragment ◽

DNA damage checkpoint pathway modulates the regulation of skeletal growth and osteoblastic bone formation by parathyroid hormone-related peptide

International Journal of Biological Sciences ◽

10.7150/ijbs.23318 ◽

2018 ◽

Vol 14 (5) ◽

pp. 508-517 ◽

Cited By ~ 7

Author(s):

Ying Zhang ◽

Guangpei Chen ◽

Zhen Gu ◽

Haijian Sun ◽

Andrew Karaplis ◽

...

Keyword(s):

Dna Damage ◽

Parathyroid Hormone ◽

Bone Formation ◽

Skeletal Growth ◽

Dna Damage Checkpoint ◽

Related Peptide ◽

Osteoblastic Bone Formation ◽

Checkpoint Pathway ◽