scholarly journals Molecular Genetics Evidence for thein VivoRoles of the Two Major NADPH-dependent Disulfide Reductases in the Malaria Parasite

2010 ◽  
Vol 285 (48) ◽  
pp. 37388-37395 ◽  
Author(s):  
Kathrin Buchholz ◽  
Elyzana D. Putrianti ◽  
Stefan Rahlfs ◽  
R. Heiner Schirmer ◽  
Katja Becker ◽  
...  
Author(s):  
W. Bernard

In comparison to many other fields of ultrastructural research in Cell Biology, the successful exploration of genes and gene activity with the electron microscope in higher organisms is a late conquest. Nucleic acid molecules of Prokaryotes could be successfully visualized already since the early sixties, thanks to the Kleinschmidt spreading technique - and much basic information was obtained concerning the shape, length, molecular weight of viral, mitochondrial and chloroplast nucleic acid. Later, additonal methods revealed denaturation profiles, distinction between single and double strandedness and the use of heteroduplexes-led to gene mapping of relatively simple systems carried out in close connection with other methods of molecular genetics.


1992 ◽  
Vol 25 (5) ◽  
pp. 995-1009
Author(s):  
Michael J. Lanser
Keyword(s):  

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