Protein Kinase C-α Regulates Insulin Action and Degradation by Interacting with Insulin Receptor Substrate-1 and 14-3-3ϵ

Francesco Oriente; Francesco Andreozzi; Chiara Romano; Giuseppe Perruolo; Anna Perfetti; Francesca Fiory; Claudia Miele; Francesco Beguinot; Pietro Formisano

doi:10.1074/jbc.m508570200

Protein Kinase C-α Regulates Insulin Action and Degradation by Interacting with Insulin Receptor Substrate-1 and 14-3-3ϵ

Journal of Biological Chemistry ◽

10.1074/jbc.m508570200 ◽

2005 ◽

Vol 280 (49) ◽

pp. 40642-40649 ◽

Cited By ~ 30

Author(s):

Francesco Oriente ◽

Francesco Andreozzi ◽

Chiara Romano ◽

Giuseppe Perruolo ◽

Anna Perfetti ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Insulin Action ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Shp2 Is Required for Protein Kinase C-dependent Phosphorylation of Serine 307 in Insulin Receptor Substrate-1

Journal of Biological Chemistry ◽

10.1074/jbc.m506549200 ◽

2005 ◽

Vol 280 (38) ◽

pp. 32693-32699 ◽

Cited By ~ 21

Author(s):

Karsten Müssig ◽

Harald Staiger ◽

Hendrik Fiedler ◽

Klaus Moeschel ◽

Alexander Beck ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Protein Kinase C Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation Requires Serine 612†

Biochemistry ◽

10.1021/bi971157f ◽

1997 ◽

Vol 36 (42) ◽

pp. 12939-12947 ◽

Cited By ~ 169

Author(s):

Kathryn De Fea ◽

Richard A. Roth

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Tyrosine Phosphorylation ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Phosphorylation of Ser357of Rat Insulin Receptor Substrate-1 Mediates Adverse Effects of Protein Kinase C-δ on Insulin Action in Skeletal Muscle Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m708588200 ◽

2008 ◽

Vol 283 (17) ◽

pp. 11226-11233 ◽

Cited By ~ 30

Author(s):

Rizwana Sanaullah Waraich ◽

Cora Weigert ◽

Hubert Kalbacher ◽

Anita M. Hennige ◽

Stefan Z. Lutz ◽

...

Keyword(s):

Skeletal Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Adverse Effects ◽

Insulin Receptor ◽

Insulin Action ◽

Muscle Cells ◽

Skeletal Muscle Cells ◽

Insulin Receptor Substrate ◽

Kinase C

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Protein Kinase C-ζ Phosphorylates Insulin Receptor Substrate-1 and Impairs Its Ability to Activate Phosphatidylinositol 3-Kinase in Response to Insulin

Journal of Biological Chemistry ◽

10.1074/jbc.m007231200 ◽

2000 ◽

Vol 276 (5) ◽

pp. 3543-3549 ◽

Cited By ~ 171

Author(s):

Lingamanaidu V. Ravichandran ◽

Diana L. Esposito ◽

Judy Chen ◽

Michael J. Quon

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Insulin Receptor Substrate ◽

Phosphatidylinositol 3 Kinase ◽

Insulin Receptor Substrate 1 ◽

Kinase C ◽

Phosphatidylinositol 3

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Protein kinase C-ζ phosphorylates serine/threonine residues at the C-terminal binding motif of the tyrosine phosphatase SHP-2 of insulin receptor substrate 1

Signal Transduction ◽

10.1002/1615-4061(200205)2:1/2<40::aid-sita40>3.0.co;2-k ◽

2002 ◽

Vol 2 (1-2) ◽

pp. 40-45

Author(s):

Rainer Lehmann ◽

Alexander Beck ◽

Klaus Moeschel ◽

Eckhart K. Schmidt ◽

Martin Deeg ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Tyrosine Phosphatase ◽

Binding Motif ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Regulation of Insulin Receptor Substrate 1 Pleckstrin Homology Domain by Protein Kinase C: Role of Serine 24 Phosphorylation

Molecular Endocrinology ◽

10.1210/me.2005-0536 ◽

2006 ◽

Vol 20 (8) ◽

pp. 1838-1852 ◽

Cited By ~ 37

Author(s):

Ranmali Nawaratne ◽

Alexander Gray ◽

Christina H. Jørgensen ◽

C. Peter Downes ◽

Kenneth Siddle ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Pleckstrin Homology Domain ◽

Insulin Receptor Substrate ◽

Pleckstrin Homology ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Protein Kinase C-ζ-induced Phosphorylation of Ser318in Insulin Receptor Substrate-1 (IRS-1) Attenuates the Interaction with the Insulin Receptor and the Tyrosine Phosphorylation of IRS-1

Journal of Biological Chemistry ◽

10.1074/jbc.m402477200 ◽

2004 ◽

Vol 279 (24) ◽

pp. 25157-25163 ◽

Cited By ~ 87

Author(s):

Klaus Moeschel ◽

Alexander Beck ◽

Cora Weigert ◽

Reiner Lammers ◽

Hubert Kalbacher ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Tyrosine Phosphorylation ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Tissue-Specific Differences in Activation of Atypical Protein Kinase C and Protein Kinase B in Muscle, Liver, and Adipocytes of Insulin Receptor Substrate-1 Knockout Mice

Molecular Endocrinology ◽

10.1210/me.2004-0045 ◽

2004 ◽

Vol 18 (10) ◽

pp. 2513-2521 ◽

Cited By ~ 32

Author(s):

Mini P. Sajan ◽

Mary L. Standaert ◽

Atsushi Miura ◽

C. Ron Kahn ◽

Robert V. Farese

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Knockout Mice ◽

Protein Kinase B ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Tissue Specific ◽

Atypical Protein Kinase ◽

Kinase C

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In Vitro Phosphorylation of Insulin Receptor Substrate 1 by Protein Kinase C-ζ: Functional Analysis and Identification of Novel Phosphorylation Sites†

Biochemistry ◽

10.1021/bi049640v ◽

2004 ◽

Vol 43 (19) ◽

pp. 5888-5901 ◽

Cited By ~ 21

Author(s):

Mark R. Sommerfeld ◽

Sabine Metzger ◽

Magdalene Stosik ◽

Norbert Tennagels ◽

Jürgen Eckel

Keyword(s):

Functional Analysis ◽

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Insulin Receptor Substrate ◽

Phosphorylation Sites ◽

Insulin Receptor Substrate 1 ◽

Kinase C

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Activation of protein kinase C alpha inhibits insulin-stimulated tyrosine phosphorylation of insulin receptor substrate-1

Molecular Endocrinology ◽

10.1210/me.8.1.51 ◽

1994 ◽

Vol 8 (1) ◽

pp. 51-58 ◽

Cited By ~ 27

Author(s):

J. E. Chin

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Insulin Receptor ◽

Tyrosine Phosphorylation ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase C ◽

Protein Kinase C Alpha

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