Brain metastases from early stage endometrial carcinoma 8 years after primary treatment: case report and review of the literature

2006 ◽  
Vol 85 (7) ◽  
pp. 890-891 ◽  
Author(s):  
Wen-Jui Lee ◽  
Chi-Hau Chen ◽  
Song-Nan Chow
Author(s):  
Leonardo Muratori ◽  
Paola Sperone ◽  
Gabriella Gorzegno ◽  
Anna La Salvia ◽  
Giorgio Vittorio Scagliotti

Abstract Background Endometrial carcinoma is one of the most common female cancers in developed countries. Disease stage is associated with the risk of disease relapse after radical treatment. Typically, the risk of disease relapse peaks at 3 years from local radical treatment and then diminishes over time, so that late relapses (i.e., from year 5 afterward) are extremely infrequent. Here, we report two cases of women with endometrial cancer who developed a disease relapse more than 15 years after radical treatment. A review of the literature revealed other seven reports of women with relapse from endometrial cancer occurring more than 10 years after radical treatment. Case presentation Case report 1 is a 56-year-old woman with an endometrioid cancer who underwent a hysterectomy with bilateral salpingo-oophorectomy in 1998. She relapsed in the lung in 2014, 16 years from radical surgery. Case report 2, a 75-year-old woman, with an endometrioid cancer, was treated by hysterectomy with bilateral salpingo-oophorectomy and adjuvant radiotherapy. The disease relapse in the lung was detected in 2019, 22 years from radical treatment. Conclusion Although guidelines do not support oncological follow-up beyond 5 years from surgery, oncologists should consider late recurrence of endometrial carcinoma in the differential diagnosis of women presenting with metastases of uncertain origin and prior history of this disease.


1989 ◽  
Vol 34 (2) ◽  
pp. 244-248 ◽  
Author(s):  
Joseph R. Vardi ◽  
Gamal H. Tadros ◽  
Simindokht Zafaranloo ◽  
Lakshim Kapadia ◽  
Martha N. Alderete ◽  
...  

2017 ◽  
Vol 32 ◽  
pp. 12-15 ◽  
Author(s):  
Shomaila Amir M. Akbar ◽  
Mutahir A. Tunio ◽  
Wafa AlShakweer ◽  
AbdulAziz AlObaid ◽  
Mushabbab AlAsiri

2012 ◽  
Vol 38 (5) ◽  
pp. 892-898 ◽  
Author(s):  
Giuseppe Vizzielli ◽  
Francesco Fanfani ◽  
Barbara Costantini ◽  
Valerio Gallotta ◽  
Giovanni Scambia ◽  
...  

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