Change of Guinea Pig Inner Ear Pressure by Square Wave Middle Ear Cavity Pressure Variation

2002 ◽  
Vol 122 (2) ◽  
pp. 138-145 ◽  
Author(s):  
R. A. Feijen ◽  
J. M. Segenhout ◽  
F. W. J. Albers ◽  
H. P. Wit
Keyword(s):  
Guinea Pig ◽  
Inner Ear ◽  
Middle Ear ◽  
Pressure Variation ◽  
Cavity Pressure ◽  
Square Wave ◽  
Inner Ear Pressure

Effect of Increased Inner Ear Pressure on Middle Ear Mechanics

1998 ◽  
Vol 118 (5) ◽  
pp. 703-708 ◽  
Author(s):  
Eugene N. Myers ◽  
Shingo Murakami ◽  
Kiyofumi Gyo ◽  
Richard L. Goode
Keyword(s):  
Inner Ear ◽  
Phase Angle ◽  
Middle Ear ◽  
Major Effect ◽  
Measuring System ◽  
Annular Ligament ◽  
Middle Ear Mechanics ◽  
Stapes Footplate ◽  
Temporal Bones ◽  
Inner Ear Pressure

Velocity of malleus, umbo, and stapes footplate in response to stepwise increases up to +400 mm H2O in hydrostatic pressure of the inner ear was investigated in 10 fresh human temporal bones by using a laser Doppler interferometer. The sound-pressure input was 114 dB SPL, and the frequency range was 0.4 to 5.0 kHz. Static displacement of these sites was also measured by a video measuring system. When the inner ear pressure was increased, the malleus and stapes moved outward. Amplitude of umbo velocity decreased below 1.0 kHz with a slight increase around 2.0 kHz, whereas stapes velocity decreased at all frequencies with the major effect below 1.0 kHz. The phase angle of malleus umbo velocity advanced markedly in response to the increased inner ear pressure between 1.0 and 1.4 kHz. Change in the vibration of the umbo was thought to be primarily caused by an increased stiffness of the middle ear conduction system, and that of the stapes was caused by distention of the annular ligament and increased cochlear impedance produced by the increased inner ear pressure. These changes in TM vibration and its phase angle may help detect indirectly an elevation of inner ear pressure. (Otolaryngol Head Neck Surg 1998;118:703–8.)

Otosurgical Model in the Guinea Pig (Cavia porcellus)

1986 ◽  
Vol 95 (4) ◽  
pp. 450-457 ◽  
Author(s):  
James R. Wells ◽  
William H. Gernon ◽  
George Warp ◽  
R. Kim Davis ◽  
Leonard L. Hays
Keyword(s):  
Animal Model ◽  
Guinea Pig ◽  
Inner Ear ◽  
Middle Ear ◽  
Surgical Anatomy ◽  
Cavia Porcellus ◽  
Middle Ear Disease ◽  
Common Problems ◽  
Lack Of Knowledge

The guinea pig is a useful model for otologic research. Common problems encountered In working with Individual animals include preexisting chronic middle ear disease, anesthetic deaths, and a lack of knowledge of the surgical anatomy and landmarks of the middle and inner ear. The methods detailed in this article will benefit those interested In a reliable, inexpensive, otosurgical animal model.

Dynamics of Inner Ear Pressure Change Caused by Intracranial Pressure Manipulation in the Guinea Pig

2001 ◽  
Vol 121 (4) ◽  
pp. 470-476 ◽  
Author(s):  
E.O. Thalen ◽  
H.P. Wit ◽  
J.M. Segenhout ◽  
F.W.J. Albers
Keyword(s):  
Intracranial Pressure ◽  
Guinea Pig ◽  
Inner Ear ◽  
Pressure Change ◽  
Inner Ear Pressure

Dynamics of Inner Ear Pressure Change Caused by Intracranial Pressure Manipulation in the Guinea Pig

2001 ◽  
Vol 121 (4) ◽  
pp. 470-476 ◽  
Author(s):  
E.O. Thalen ◽  
H.P. Wit ◽  
J.M. Segenhout ◽  
F.W.J. Albers
Keyword(s):  
Intracranial Pressure ◽  
Guinea Pig ◽  
Inner Ear ◽  
Pressure Change ◽  
Inner Ear Pressure

An Ultrastructural and Functional Study of the Inner Ear after Administration of Hyaluronan into the Middle Ear of the Guinea Pig

1987 ◽  
Vol 104 (sup442) ◽  
pp. 66-71 ◽  
Author(s):  
B. Engström ◽  
S. Bjurström ◽  
B. Jansson ◽  
H. Engström ◽  
C. Angelborg
Keyword(s):  
Guinea Pig ◽  
Inner Ear ◽  
Middle Ear ◽  
Functional Study

Dynamics of inner ear pressure release, measured with a double-barreled micropipette in the guinea pig

1999 ◽  
Vol 132 (1-2) ◽  
pp. 131-139 ◽  
Author(s):  
Hero P. Wit ◽  
Elisabeth O. Thalen ◽  
Frans W.J. Albers
Keyword(s):  
Guinea Pig ◽  
Inner Ear ◽  
Pressure Release ◽  
Inner Ear Pressure

Effect of increased inner ear pressure on middle ear mechanics☆☆☆★

1998 ◽  
Vol 118 (5) ◽  
pp. 703-708 ◽  
Author(s):  
SHINGO MURAKAMI ◽  
KIYOFUMI GYO ◽  
RICHARD L. GOODE
Keyword(s):  
Inner Ear ◽  
Middle Ear ◽  
Middle Ear Mechanics ◽  
Inner Ear Pressure
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