Oxidative stress and cytogenetic effects in root tip cells of Allium cepa L. induced by alcoholic extracts of Leptinotarsa decemlineata (Say)

Caryologia ◽  
2018 ◽  
Vol 71 (4) ◽  
pp. 405-413
Author(s):  
Nicoleta Anca Şuţan ◽  
Georgiana Uţă ◽  
Daniela Bărbuceanu
2010 ◽  
Vol 6 ◽  
pp. 4-7 ◽  
Author(s):  
Archana Pandey ◽  
Shyam R Sakya

Effect of triazophos (an organophosphorous insecticide) on mitotic activity and chromosomal behavior in the meristematic region of root tip cells of Allium cepa L. was assessed. The insecticide showed mitotic depression and positive chromo-toxic effects. Abnormalities, such as stickiness, plasmolysed cells, equatorial plate shifting, polar shifting, irregular chromosome arrangement, precocious arms formation, bridge formation, C-metaphase, fragmentation of chromosomes, unequal cytokinesis, diagonal cytokinesis, delayed cytokinesis and formation of binucleated cells, were recorded in the chemically pretreated root meristem. Key-words: chromosomal and cellular abnormalities; cytotoxic effect; mitotic index; phase indices.DOI: 10.3126/botor.v6i0.2903 Botanica Orientalis - Journal of Plant Science (2009) 6: 4-7


Genetika ◽  
2009 ◽  
Vol 41 (2) ◽  
pp. 179-188 ◽  
Author(s):  
Vanya Kalcheva ◽  
Asya Dragoeva ◽  
Karamfil Kalchev ◽  
Dobromir Enchev

The chemistry of organophosphorus compounds is a subject of increasing interest and different new compounds have been synthesized. There are data that some known organophosphates are mutagens. Oxaphosphole derivatives possess biological activity and might influence proliferating cells. Bioassays are currently used in ecotoxicology to investigate the effects and mechanisms of action of new chemicals. To provide a broad coverage of the mutagenic potential of a chemical, information on different experimental test-systems is required. Genotoxicity assays are usually performed at high doses, but humans are exposed to most environmental chemicals at low doses. The objective of this study was to determine the genotoxicity of low doses (2.82x10-6 ?g/kg and 2.82x10-9 ?g/kg, corresponding to concentrations 10-12M and 10-15M) of 4-bromo-N,N-diethyl- 5,5-dimethyl-2,5-dihydro-1,2-oxaphosphol-2-amine 2-oxide (Br-oxph) in ICR mice bone marrow cells and Allium cepa L. root tip cells. Treatment with Br-oxph for 3 h produced alterations in the mitotic index in Allium cepa cells and induced chromosome aberrations in both test systems. These effects remained 48 h after the treatment. The data from the study showed the existence of cytotoxic and genotoxic effects of Br-oxph at tested doses.


2013 ◽  
Vol 67 (6) ◽  
pp. 388 ◽  
Author(s):  
Hilada Nefic ◽  
Jasmin Musanovic ◽  
Azra Metovic ◽  
Kemajl Kurteshi

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