An Improved Process for Synthesis of (S)-Duloxetine Hydrochloride Involving Enzymatic Asymmetric Carbonyl Reduction on a Novel Ketoamine

2020 ◽  
Vol 53 (1) ◽  
pp. 1-8
Author(s):  
Sachin A. Sasane ◽  
Mofazzal Husain ◽  
Nandu B. Bhise ◽  
Girij P. Singh ◽  
Alex Joseph ◽  
...  
Keyword(s):  
Duloxetine Hydrochloride ◽  
Carbonyl Reduction

Activation of sodium borohydride via carbonyl reduction for the synthesis of amine- and phosphine-boranes

2021 ◽  
Author(s):  
P. Veeraghavan Ramachandran ◽  
Henry Hamann ◽  
Randy Lin
Keyword(s):  
Carbon Dioxide ◽  
Sodium Borohydride ◽  
Metathesis Reaction ◽  
Carbonyl Reduction ◽  
Amine Boranes

A highly versatile synthesis of amine-boranes via carbonyl reduction by sodium borohydride is described. Unlike the prior bicarbonate-mediated protocol, which proceeds via a salt metathesis reaction, the carbon dioxide-mediated synthesis...

Homologies between enzymes involved in steroid and xenobiotic carbonyl reduction in vertebrates, invertebrates and procaryonts

1992 ◽  
Vol 43 (7) ◽  
pp. 665-675 ◽  
Author(s):  
Udo C.T. Oppermann ◽  
Edmun Maser ◽  
J.J.R. Hermans ◽  
Jan Koolman ◽  
Karl J. Netter
Keyword(s):  
Carbonyl Reduction
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