Transvaginal ultrasound measurement of endometrial thickness and endometrial pipelle sampling as an alternative diagnostic procedure to hysteroscopy and dilatation and curettage in the management of post-menopausal bleeding

1997 ◽  
Vol 17 (4) ◽  
pp. 399-402 ◽  
Author(s):  
B. Y. De Silva ◽  
K. Stewart ◽  
J. D. Steven ◽  
M. Sathanandan
Keyword(s):  
Diagnostic Procedure ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Ultrasound Measurement ◽  
Dilatation And Curettage ◽  
Post Menopausal

scholarly journals Co-relation of endometrial thickness by transvaginal sonogram with histopathology pattern in abnormal uterine bleeding: a study from South India

2020 ◽  
Vol 9 (4) ◽  
pp. 1416
Author(s):  
Chippy Tess Mathew ◽  
Uma Maheswari ◽  
Karthikeyan Shanmugam
Keyword(s):  
Precancerous Lesions ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Endometrial Sampling ◽  
Dilatation And Curettage ◽  
Number Of Patients ◽  
Fourth Decade ◽  
Proliferative Endometrium

Background: Under normal circumstances, a woman's uterus sheds a limited amount of blood during each menstrual period (around 80 ml). Bleeding that occurs erratically or excessive menstrual bleeding is called abnormal uterine bleeding (AUB). The causes of AUB are many and varied. Initial investigations include transvaginal ultrasound and histopathologic assessment of the endometrium. Objective of this study was to evaluation of endometrial thickness with trans-vaginal ultrasound and its correlation with histopathology by dilatation and curettage in abnormal uterine bleeding. To determine the efficacy of transvaginal ultrasound in evaluating the endometrial thickness. To correlate the endometrial thickness by transvaginal ultrasound with endometrial histopathology in women with AUB.Methods: It is a retrospective observational study. All reproductive and perimenopausal age group women who underwent dilatation and curettage for abnormal uterine bleeding during the period June 2014-June 2016 was taken and analyzed and correlated with their endometrial thickness measured with Transvaginal ultrasound.Results: Around 478 patients who underwent endometrial sampling over a period of two years were analyzed. Maximum number of patients were in the fourth decade and the overweight category 36.6%. Proliferative endometrium was the most common histopathologic picture (44.76%). Detection of precancerous lesions were-5.87% and endometrial cancer was 1.05%.Conclusions: An ET of 8 mm and above gave 100% sensitivity and negative predictive value for precancerous and cancerous lesions.

scholarly journals Role of transvaginal ultrasound in assessment of endometrial pathology in patients with post-menopausal bleeding

2017 ◽  
Vol 6 (4) ◽  
pp. 1376 ◽  
Author(s):  
Sudha Menon ◽  
Sreekumari R
Keyword(s):  
Diagnostic Tool ◽  
Histopathological Examination ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Characteristic Curve ◽  
High Sensitivity ◽  
High Negative Predictive Value ◽  
Post Menopausal ◽  
A Prospective Study ◽  
Endometrial Pathology

Background: Post-menopausal bleeding (PMB) is the most distressing problem in females Endometrial thickness (EMT) as assessed by transvaginal ultrasound (TVS) aids in diagnosing endometrial pathology. This study analyses usefulness of TVS as a diagnostic tool in the evaluation of PMB.Methods: A prospective study was conducted in 100 patients. Correlation of EMT by TVS was compared with gold standard of histopathological examination (HPE) of the endometrium by fractional curettage (FC).Results: Mean age was 56.9±8.03 years and mean parity status was 2.83±1.45. Mean duration after menopause to presentation of bleeding per vaginum was 5.7±3.85 years. As per the receiver operating characteristic curve (ROC) analysis, an EMT of 10.8 mm had a high negative predictive value (99.1%) for malignancy with moderate specificity (62.79%) and high sensitivity (92.3%).Conclusions: TVS can be easily performed and is less expensive and a useful diagnostic tool in the evaluation of PMB with a cut off value of 10.8 mm EMT gives a high sensitivity (92.3%) and moderate specificity (62.79%).

scholarly journals Diagnostic efficacy of gel infusion sonography in post-menopausal bleeding

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Shimaa Abdalla Ahmed ◽  
Hisham Abo-Taleb
Keyword(s):  
Diagnostic Accuracy ◽  
Real Time ◽  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Screening Method ◽  
Observer Agreement ◽  
Diagnostic Efficiency ◽  
Offline Analysis ◽  
Post Menopausal ◽  
Time Evaluation

Abstract Background Our purpose was to evaluate the diagnostic performance of two-dimensional transvaginal ultrasound (2D-TVUS) and gel infusion sonography (GIS) at offline analysis for endometrial characterization compared with real-time evaluation during scanning. One hundred fifty women presented with PMB. At TVUS, endometrial thickness was ≥ 4 mm in 122 (81.3%) women and < 4 mm in 28 (18.72%). Among 122 women with endometrial thickness > 4 mm, GIS was successfully performed in 117 (95.9%). Examinations were stored as video clips for later evaluation (offline analysis) by two less experienced radiologists. Endometrial lesions were classified into four categories: no endometrial abnormality, hyperplasia, polyps, and cancer. Diagnostic efficiency of real-time and offline analysis for diagnosis of each category was calculated and compared, and inter-observer agreement for offline analysis was calculated. Results All patients underwent hysteroscopy and/or hysterectomy. Histopathological results confirmed no endometrial abnormality in (27.3%, 41/150), endometrial hyperplasia in (12.7%, 19/150), endometrial polyps in (17.3%, 26/150), and endometrial cancer in (42.7%, 64/150). Overall diagnostic accuracy of real-time imaging was 89.7% (CI 84–91%)). The highest accuracy 92.7% (CI 88–98%) was seen in the diagnosis of cancer, and polyps 91.5% (CI 86–97%). The lowest accuracy 75% (CI 69–82%) was seen in hyperplasia. Overall diagnostic accuracy of offline analysis was 81%, and it increased to 88% (CI 83–92%) after a restricted analysis of good quality clips. The highest accuracy 90.7% (CI 83–95%) was seen in the diagnosis of polyps, and cancer 90.4% (CI 83–96%). The lowest accuracy 71% (CI 69–75%) was seen in hyperplasia. At offline analysis, the inter-observer agreement was substantial k = 0.77 (CI 71–84) in the evaluation of four endometrial categories after the exclusion of bad quality videos. It was excellent in exclusion of endometrial abnormalities k = 0.85 (0.78–0.90), substantial in the diagnosis of polyps k = 0.71 (0.69–0.88), cancer k = 0.61 (0.61–0.77), and moderate in the diagnosis of hyperplasia k = 0.41 (0.30–0.41). Conclusion Offline 2D analysis with a good image quality has comparable accuracy to a real-time evaluation during scanning in the diagnosis of endometrial lesions. It can increase the accuracy of sonography in ruling out endometrial abnormalities and diagnose non-hyperplastic endometrial pathologies. High NPV and substantial reproducibility can make it an efficient initial screening method in a post-menopausal bleeding.

Ultrasound Measurement of Endometrial Thickness for Detecting Endometrial Malignancy

2021 ◽  
Vol 15 (6) ◽  
pp. 1136-1138
Author(s):  
A. Iqbal ◽  
S. K S Murrium ◽  
M. Yaseen ◽  
K. Shakeel ◽  
M. Z Iqbal
Keyword(s):  
Endometrial Cancer ◽  
Systematic Reviews ◽  
Endometrial Thickness ◽  
Uterine Bleeding ◽  
Systemic Review ◽  
Ultrasound Measurement ◽  
Gynecologic Malignancy ◽  
Thin Endometrium ◽  
Post Menopausal ◽  
Web Research

Background: Post-menopausal Bleeding is extremely doubtful of existence a mark intended for incidence of EC as well as around 5% to 12% of post-menopausal bleeding consequences commencing endometrial cancer. EC is greatest communal Gynecologic Malignancy into established countries. Thin endometrium (≤4 mm) devours precise high NPV (99%). Thickened Endometrium has been considered by way of sign intended for an offensive assessment. Aim: To determine the ET measurement for detecting endometrial malignancy with uterine bleeding in post-menopausal females. Methods: The search was led according to Systematic Reviews Ethics. Searched databases were: Google scholar and Web Research from January 2014 and November 2020. Around nine studies were designated for this Systemic Review. We mined subsequent facts: Design of study, mean age and range, menopause duration, range and mean, BMI range and mean, as well as ET range and mean. Conclusion: From beyond examination this review concluded that, the Endometrial Thickness among the suggested alteration in cut off 3-5 mm within repetitive ultrasound practice must be ended in elevation threat females identify for malignancy before in Postmenopausal females as well as ultrasound is attested chosen a convenient implement to diagnose. Keywords: Post-menopausal Bleeding, Endometrial Thickness, Endometrial Cancer.

scholarly journals Ultrasound Measurement of Endometrial Thickness for Detecting Endometrial Malignancy with Uterine Bleeding in Postmenopausal Women- A Systematic Review

2021 ◽  
Vol 15 (7) ◽  
pp. 1461-1463
Author(s):  
Alia Iqbal ◽  
Syeda Khadija-Tul-Sughra Murrium ◽  
Maria Yaseen ◽  
Kiran Shakeel ◽  
Muhammad Zafar Iqbal
Keyword(s):  
Systematic Review ◽  
Endometrial Cancer ◽  
Endometrial Thickness ◽  
Uterine Bleeding ◽  
Systemic Review ◽  
Ultrasound Measurement ◽  
Gynecologic Malignancy ◽  
Thin Endometrium ◽  
Post Menopausal ◽  
Web Research

Background: Post-menopausal Bleeding is extremely doubtful of existence a mark intended for incidence of EC as well as around 5% to 12% of post-menopausal bleeding consequences commencing endometrial cancer. EC is greatest communal Gynecologic Malignancy into established countries. Thin endometrium (≤4 mm) devours precise high NPV (99%). Thickened Endometrium has been considered by way of sign intended for an offensive assessment. Aim: To determine the ET measurement for detecting endometrial malignancy with uterine bleeding in post-menopausal females. Methods: The search was led according to Systematic Reviews Ethics. Searched databases were: Google scholar and Web Research from January 2014 and November 2020. Around nine studies were designated for this Systemic Review. We mined subsequent facts: Design of study, mean age and range, menopause duration, range and mean, BMI range and mean, as well as ET range and mean. Conclusion: From beyond examination this review concluded that, the Endometrial Thickness among the suggested alteration in cut off 3-5 mm within repetitive ultrasound practice must be ended in elevation threat females identify for malignancy before in Postmenopausal females as well as ultrasound is attested chosen a convenient implement to diagnose. Keywords: Post-menopausal Bleeding, Endometrial Thickness, Endometrial Cancer.

Post-menopausal bleeding – Is transvaginal ultrasound a useful first-line investigation in tamoxifen users?

2018 ◽  
Vol 24 (2) ◽  
pp. 72-78 ◽  
Author(s):  
A Abdaal ◽  
Y Mushtaq ◽  
L Khasati ◽  
J Moneim ◽  
F Khan ◽  
...  
Keyword(s):  
Endometrial Thickness ◽  
Transvaginal Ultrasound ◽  
Outcome Data ◽  
Tamoxifen Treatment ◽  
First Line ◽  
Tamoxifen Group ◽  
History Of ◽  
Post Menopausal ◽  
Endometrial Pathology

Objective To evaluate the role of transvaginal ultrasound triage in women with a history of tamoxifen treatment who present with post-menopausal bleeding. Study design A retrospective review was undertaken of patients who presented with symptoms of post-menopausal bleeding and underwent ultrasound triage. Endometrial thickness and ultrasonographic features were then correlated with hysteroscopic and histopathological outcome data. The findings and outcomes for women with a history of tamoxifen use (tamoxifen group) were compared to those who had not taken tamoxifen (non-tamoxifen group). Results A total of 614 women with post-menopausal bleeding underwent transvaginal ultrasound triage, of whom 53 had a history of current or previous tamoxifen treatment. An endometrial thickness of ≥5 mm or the presence of other abnormal features was used to triage women to further investigation by hysteroscopy and biopsy. Endometrial thickness was significantly greater in the tamoxifen group (11 mm vs. 6 mm). Nearly all of the tamoxifen group were triaged to further investigation (98.1%), compared with significantly fewer in the non-tamoxifen group (68.3%) Overall, the incidence of endometrial pathology was also significantly higher in tamoxifen patients (43.4% vs. 31.7%). Conclusion For women presenting with post-menopausal bleeding, the use of transvaginal ultrasound as a triage tool is rarely helpful in evaluating women who have a history as tamoxifen use, as most will require further investigation with hysteroscopy and biopsy. A post-menopausal bleeding protocol that omits transvaginal ultrasound for women with a history of tamoxifen use may be an appropriate and effective pathway for managing these patients.

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