Optimal Estimation of Genetic Relatedness in High-Dimensional Linear Models

2018 ◽  
Vol 114 (525) ◽  
pp. 358-369 ◽  
Author(s):  
Zijian Guo ◽  
Wanjie Wang ◽  
T. Tony Cai ◽  
Hongzhe Li
2019 ◽  
Vol 116 (12) ◽  
pp. 5451-5460 ◽  
Author(s):  
Jean Barbier ◽  
Florent Krzakala ◽  
Nicolas Macris ◽  
Léo Miolane ◽  
Lenka Zdeborová

Generalized linear models (GLMs) are used in high-dimensional machine learning, statistics, communications, and signal processing. In this paper we analyze GLMs when the data matrix is random, as relevant in problems such as compressed sensing, error-correcting codes, or benchmark models in neural networks. We evaluate the mutual information (or “free entropy”) from which we deduce the Bayes-optimal estimation and generalization errors. Our analysis applies to the high-dimensional limit where both the number of samples and the dimension are large and their ratio is fixed. Nonrigorous predictions for the optimal errors existed for special cases of GLMs, e.g., for the perceptron, in the field of statistical physics based on the so-called replica method. Our present paper rigorously establishes those decades-old conjectures and brings forward their algorithmic interpretation in terms of performance of the generalized approximate message-passing algorithm. Furthermore, we tightly characterize, for many learning problems, regions of parameters for which this algorithm achieves the optimal performance and locate the associated sharp phase transitions separating learnable and nonlearnable regions. We believe that this random version of GLMs can serve as a challenging benchmark for multipurpose algorithms.


Biometrics ◽  
2019 ◽  
Vol 75 (2) ◽  
pp. 551-561
Author(s):  
Zhe Fei ◽  
Ji Zhu ◽  
Moulinath Banerjee ◽  
Yi Li

2012 ◽  
Vol 55 (2) ◽  
pp. 327-347 ◽  
Author(s):  
Dengke Xu ◽  
Zhongzhan Zhang ◽  
Liucang Wu

2013 ◽  
Vol 143 (9) ◽  
pp. 1417-1438 ◽  
Author(s):  
Mathilde Mougeot ◽  
Dominique Picard ◽  
Karine Tribouley

2018 ◽  
Vol 46 (1) ◽  
pp. 289-313
Author(s):  
Charles‐Elie Rabier ◽  
Brigitte Mangin ◽  
Simona Grusea

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