Evaluation of Bronchial Hyperresponsiveness by Monitoring of Transcutaneous Oxygen Tension and Arterial Oxygen Saturation during Methacholine Challenge in Asthmatic Children

2006 ◽  
Vol 43 (2) ◽  
pp. 145-149 ◽  
Author(s):  
Junying Wang ◽  
Hiroyuki Mochizuki ◽  
Reiko Muramatsu ◽  
Hirokazu Arakawa ◽  
Kenichi Tokuyama ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Oxygen Tension ◽  
Arterial Oxygen Saturation ◽  
Bronchial Hyperresponsiveness ◽  
Arterial Oxygen ◽  
Methacholine Challenge ◽  
Transcutaneous Oxygen Tension ◽  
Transcutaneous Oxygen ◽  
Asthmatic Children

Transcutaneous Determination of Arterial Oxygen Tension

PEDIATRICS ◽  
1975 ◽  
Vol 55 (2) ◽  
pp. 224-231
Author(s):  
A. Fenner ◽  
R. Müller ◽  
H. G. Busse ◽  
M. Junge ◽  
J. Wolfsdorf
Keyword(s):  
Oxygen Tension ◽  
Newborn Infants ◽  
Arterial Oxygen Tension ◽  
Correlation Coefficients ◽  
Arterial Oxygen ◽  
Transcutaneous Oxygen Tension ◽  
Term Infants ◽  
Transcutaneous Oxygen ◽  
Developed Surface ◽  
Cutaneous Perfusion

Arterial oxygen tension measurements were performed simultaneously using two different techniques: (1) the conventional method of analyzing a blood sample obtained from the radial artery by means of a Clark electrode and (2) a new method of transcutaneous oxygen tension recording using a newly developed surface electrode containing a built-in heating device to ensure optimal cutaneous perfusion at the site of measurement. Two groups of newborn infants were used as subjects: (1) 70 clinically healthy babies who were tested during normoxia and hyperoxia (breathing 80% to 100% oxygen) and (2) 20 sick preterm and term infants receiving inspired oxygen concentrations of between 21% and 100% during the measurement. Our results indicate a satisfactory accuracy for the transcutaneous oxygen tension measurements in normoxia and hyperoxia (percentage coefficient of variation, 15.9% and 24.1%, respectively). In hypoxia agreement between the two methods varies depending on the degree of circulatory derangement. Overall correlation coefficients were greater than 0.85 in each group.

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