The study proposed adaptive wavelet neural network controller can achieve good and precise welding control performance and use synchrotron radiation research center developed multi-gun group automatic welding system to verify the validity of the research method. Multi-gun group welding system is applied in Taiwan Photon Source (TPS). Storage ring aluminum alloy vacuum chamber of Taiwan Photon Source .In the past aluminum alloy vacuum chamber welding, it all depends on the empirical welding rule of operator to give appropriate welding current, argon flow, wire feed speed and welding speed for control. Therefore, the paper uses automatic welding skill, which takes National Instruments PXI-8180 system as basic structure, and adaptive wavelet neural network controlled four optimized parameters, I.E. welding current, wire feed speed, flow rate of argon gas and welding speed, The vacuum chamber pressure value is also up to 6.2X10-10Torr/mA. It is successfully applied to the TPS system. Therefore, it can prove the effectiveness and practicality of the method proposed in this study.