Impact of obesity with or without hypertension on systemic haemodynamic and renal responses to lower body negative pressure

2020 ◽  
pp. 1-8
Author(s):  
Nima Vakilzadeh ◽  
Dusan Petrovic ◽  
Marc Maillard ◽  
Lucie Favre ◽  
Eric Grouzmann ◽  
...  
1998 ◽  
Vol 31 (5) ◽  
pp. 669-676 ◽  
Author(s):  
P. Mauran ◽  
I. Pham ◽  
S. Sediame ◽  
D. Jolly ◽  
P. E. Chabrier ◽  
...  

Author(s):  
Akanksha Singh ◽  
Shival Srivastav ◽  
Kavita Yadav ◽  
Dinu S. Chandran ◽  
Ashok Kumar Jaryal ◽  
...  

1990 ◽  
Vol 78 (4) ◽  
pp. 399-401 ◽  
Author(s):  
M. J. Cullen ◽  
J. R. Cockcroft ◽  
D. J. Webb

1. Six healthy male subjects received 0.9% (w/v) NaCl (saline) followed by incremental doses of bradykinin (1, 3 and 10 pmol/min), via the left brachial artery. Blood flow and the response of blood flow to lower-body negative pressure were measured in both forearms during infusion of saline and each dose of bradykinin. 2. Bradykinin produced a moderate and dose-dependent increase in blood flow in the infused, but not the non-infused, forearm. Lower-body negative pressure produced an approximately 15–20% reduction in blood flow in both forearms, and this response was unaffected by local infusion of bradykinin. 3. Bradykinin, in contrast to angiotensin II, had no acute effect on peripheral sympathetic responses to lower-body negative pressure. We conclude that, in forearm resistance vessels in man, withdrawal of angiotensin II, rather than accumulation of bradykinin, is likely to account for the attenuation of peripheral sympathetic responses after acute administration of a converting-enzyme inhibitor.


Maturitas ◽  
2017 ◽  
Vol 103 ◽  
pp. 91
Author(s):  
Amanda Q.X. Nio ◽  
Eric J. Stöhr ◽  
Samantha Rogers ◽  
Rachel Mynors-Wallis ◽  
Jane M. Black ◽  
...  

1986 ◽  
Vol 18 (supplement) ◽  
pp. S15
Author(s):  
H. L. Smith ◽  
D. L. Hudson ◽  
H. M. Graitzer ◽  
P. B. Raven

1987 ◽  
Vol 62 (6) ◽  
pp. 2436-2441 ◽  
Author(s):  
D. L. Fryman ◽  
D. T. Frazier

Experiments were performed in eight lightly anesthetized thiopental sodium (Pentothal) cats to examine whether diaphragmatic afferents can significantly alter the neural drive to the diaphragm when the animal is exposed to lower body negative pressure. Moving-time-averaged diaphragmatic electromyograms (EMGma) were recorded and compared before and during exposure to lower body negative pressure in each of three consecutive conditions: C7 spinalization, bilateral vagotomy, and cervical dorsal rhizotomy. Application of lower body negative pressure in C7-spinalized animals resulted in a decrease in inspiratory time and peak diaphragmatic activity compared with control levels. After bilateral vagotomy, EMGma activity was prolonged with the application of lower body negative pressure. However, there was no increase in peak EMGma activity. After transection of the cervical dorsal roots subserving the phrenic nerve, the prolongation of diaphragmatic activity negative was eliminated. Therefore, we conclude that the significant increase in duration of inspiration in response to application of lower body negative pressure in the C7-spinalized, bilaterally vagotomized cat is mediated by phrenic nerve afferents.


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