acute effect
Recently Published Documents


TOTAL DOCUMENTS

2019
(FIVE YEARS 447)

H-INDEX

61
(FIVE YEARS 8)

2022 ◽  
Vol 8 ◽  
Author(s):  
Guli Xu ◽  
Yexian Yuan ◽  
Pei Luo ◽  
Jinping Yang ◽  
Jingjing Zhou ◽  
...  

Endurance training and explosive strength training, with different contraction protein and energy metabolism adaptation in skeletal muscle, are both beneficial for physical function and quality of life. Our previous study found that chronic succinate feeding enhanced the endurance exercise of mice by inducing skeletal muscle fiber-type transformation. The purpose of this study is to investigate the effect of acute succinate administration on skeletal muscle explosive strength and its potential mechanism. Succinate was injected to mature mice to explore the acute effect of succinate on skeletal muscle explosive strength. And C2C12 cells were used to verify the short-term effect of succinate on oxidative phosphorylation. Then the cells interfered with succinate receptor 1 (SUCNR1) siRNA, and the SUCNR1-GKO mouse model was used for verifying the role of SUCNR1 in succinate-induced muscle metabolism and expression and explosive strength. The results showed that acute injection of succinate remarkably improved the explosive strength in mice and also decreased the ratio of nicotinamide adenine dinucleotide (NADH) to NAD+ and increased the mitochondrial complex enzyme activity and creatine kinase (CK) activity in skeletal muscle tissue. Similarly, treatment of C2C12 cells with succinate revealed that succinate significantly enhanced oxidative phosphorylation with increased adenosine triphosphate (ATP) content, CK, and the activities of mitochondrial complex I and complex II, but with decreased lactate content, reactive oxygen species (ROS) content, and NADH/NAD+ ratio. Moreover, the succinate's effects on oxidative phosphorylation were blocked in SUCNR1-KD cells and SUCNR1-KO mice. In addition, succinate-induced explosive strength was also abolished by SUCNR1 knockout. All the results indicate that acute succinate administration increases oxidative phosphorylation and skeletal muscle explosive strength in a SUCNR1-dependent manner.


Author(s):  
Iwona Sulowska-Daszyk ◽  
Agnieszka Skiba

During long-distance running, athletes are exposed to repetitive loads. Myofascial structures are liable to long-term work, which may cause cumulating tension within them. The aim of this study was to evaluate the acute effect of self-myofascial release on muscle flexibility in long-distance runners. The study comprised 62 long-distance, recreationally running participants between the age of 20 and 45 years. The runners were randomly divided into two groups: Group 1 (n = 32), in which subjects applied the self-myofascial release technique between baseline and the second measurement of muscle flexibility, and Group 2 (n = 30), without any intervention. The self-myofascial release technique was performed according to standardized foam rolling. Assessment of muscle flexibility was conducted according to Chaitow’s proposal. After application of the self-myofascial release technique, higher values were noted for the measurements of the following muscles: piriformis, tensor fasciae latae muscles and adductor muscles. Within the iliopsoas and rectus femoris muscles, lower values were observed in the second measurement. These changes were statistically significant (p < 0.05) within the majority of muscles. All these outcomes indicate improvement related to larger muscle flexibility and also, an increase in range of motion. In the control group (Group 2), significant improvement was observed only in measurements for the iliopsoas muscles. The single application of self-myofascial release techniques with foam rollers may significantly improve muscle flexibility in long-distance runners. Based on these results, the authors recommend the self-myofascial release technique with foam rollers be incorporated in the daily training routine of long-distance runners, as well as athletes of other sport disciplines.


2022 ◽  
Vol 94 (1) ◽  
Author(s):  
ANDRÉA B.P.S. QUEIROZ ◽  
ALESSANDRA RODRIGUES ◽  
MARITA V. CARDOZO ◽  
NATÁLIA T.B. COSTA ◽  
LAURA G. SOARES ◽  
...  

2021 ◽  
Vol 25 (6) ◽  
pp. 353-358
Author(s):  
Ramazan Bayer ◽  
Özgür Eken

Background and Study Aim. Muay thai is a combat sport in which the competitors kick, punch, knee, elbow and growl with their opponents. The strength of the leg muscles can increase the intensity of the kick and its flexibility is a well-known issue for this sport. Determining the most appropriate method for these issues provides important gains to the athletes. One of the methods applied to achieve these gains is acute massage applications. The aim of the study is to evaluate the acute effect of different massage times on squat jump, countermovement jump and flexibility performance. Materials and Methods. Twelve healthy male muay thai athletes (age, 19.83± 1.46 years; height, 175.33± 7.91 cm; body mass, 65.16 ±13.36 kg) participated in the study, who exercised three times a week. The study consists of a single group. The study consists of 4 different massage duration protocols. These protocols consist of no massage (NM), five minutes massage (5MMSG), ten minutes massage (10MMSG) and fifteen minutes massage (15MMSG). Counter movement jump, squat jump, sitting and lying flexibility were measured after each massage period, respectively. All protocols were continued on consecutive days. Results. There was a significant main effect for flexibility (F = 10,872 ; p = 0.00), countermovement jump (F = 4.719 p=.008) and squat jump (F = 6.262 p=.002) performance. The best flexibility, countermovement jump and squat jump performance detected immediately after 5MMSG was respectively 35,16 ± 6,33; 37,17 ± 4,18 and next, 36,05 ± 4,68. Conclusion. As a result, it is recommended that different massage durations are effective in improving physical performance, and 5MMSG before competition is recommended for athletes and coaches to get more performance.


Sports ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 6
Author(s):  
Eirik Lindset Kristiansen ◽  
Stian Larsen ◽  
Roland van den van den Tillaar

The target of this study was to investigate the acute effect of a supramaximal augmented eccentric load on the kinematics and myoelectric activity during the concentric phase of the lift in a traditional bench press. Ten resistance-trained males (age 24 ± 6.4 years, height 1.80 ± 0.07 m, body-mass 87.2 ± 16.9 kg) performed two repetitions at 110/85% of the 1-RM in the dynamic accentuated external resistance (DAER) group and two repetitions at 85/85% of the 1-RM for the control group in a traditional bench press. The barbell kinematics, joint kinematics and myoelectric activity of eight muscles were measured in the eccentric phase and the pre-sticking, sticking and post-sticking regions. The main findings were that the sticking region started at a lower barbell height and that a lower barbell velocity was observed in the sticking region during the second repetition in the DAER condition compared to the control condition. Additionally, the lateral deltoid muscle and clavicle part of the pectoralis were more active during the eccentric loading compared to the control condition for the second repetition. Furthermore, higher myoelectric activity was measured during the second repetition in the sticking region for the eccentric loading condition in both pectoralis muscles, while the sternal parts of the pectoralis and anterior deltoid were more active during the second repetition of the control condition in the post-sticking region. Based on our findings, it can be concluded that the supramaximal loading in the descending phase with 110% of the 1-RM in the bench press does not have an acute and positive effect of enhanced performance in the ascending phase of the lift at 85% of 1-RM. Instead, fatigue occurs when using this eccentric load during a bench press.


Life ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 29
Author(s):  
Maria Chiara Pelle ◽  
Michele Provenzano ◽  
Isabella Zaffina ◽  
Roberta Pujia ◽  
Federica Giofrè ◽  
...  

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are two gut hormones, defined incretins, responsible for the amplification of insulin secretion after oral glucose intake. Unlike GLP-1, GIP has little acute effect on insulin secretion and no effect on food intake; instead it seems that the GIP may be an obesity-promoting hormone. In patients with type2 diabetes mellitus (T2DM) some studies found a downregulation of GIP receptors on pancreatic β cells caused by hyperglycemic state, but the glucagonotropic effect persisted. Agonists of the receptor for the GLP-1 have proven successful for the treatment of diabetes, since they reduce the risk for cardiovascular and renal events, but the possible application of GIP as therapy for T2DM is discussed. Moreover, the latest evidence showed a synergetic effect when GIP was combined with GLP-1 in monomolecular co-agonists. In fact, compared with the separate infusion of each hormone, the combination increased both insulin response and glucagonostatic response. In accordance with theseconsiderations, a dual GIP/GLP-1receptor agonist, i.e., Tirzepatide, known as a “twincretin” had been developed. In the pre-clinical trials, as well as Phase 1–3 clinical trials, Tirzepatideshowedpotent glucose lowering and weight loss effects within an acceptable safety.


Author(s):  
Gema Pereira-Caro ◽  
Tahani M. Almutairi ◽  
Alan Crozier ◽  
José Luis Ordoñez-Díaz ◽  
José Manuel Moreno-Rojas ◽  
...  
Keyword(s):  

Sign in / Sign up

Export Citation Format

Share Document