Long-term Follow-up of Patients with Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome

2016 ◽  
pp. 1-7 ◽  
Author(s):  
Bianka Sobolewska ◽  
Tarek Bayyoud ◽  
Christoph Deuter ◽  
Deshka Doycheva ◽  
Manfred Zierhut
Keyword(s):  
Tubulointerstitial Nephritis ◽  
Tinu Syndrome ◽  
Long Term Follow Up

scholarly journals Clinical and Genetic Features of Tubulointerstitial Nephritis and Uveitis Syndrome with Long-Term Follow-Up

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Hiroaki Kanno ◽  
Kyoko Ishida ◽  
Wataru Yamada ◽  
Ikumi Shiraki ◽  
Hiroki Murase ◽  
...  
Keyword(s):  
Tubulointerstitial Nephritis ◽  
Young Patients ◽  
Clinical Manifestations ◽  
Steroid Treatment ◽  
Hla Typing ◽  
Systemic Steroid ◽  
Long Term Follow Up ◽  
The Mean

Purpose. To investigate the clinical manifestations, prognosis, and HLA-type of tubulointerstitial nephritis and uveitis syndrome (TINU) with long-term follow-up. Methods. Clinical data of five patients with TINU were retrospectively reviewed. Results. The mean age was 15.8 years. The mean follow-up periods were 54.0 months. The initial subjective symptoms were bulbar injection (100%), ocular pain (80%), and blurred vision (60%). The medical department that the patients visited first was ophthalmology in 4 (80%) cases. Urinalysis showed the characteristic increase of the β2 microglobulin in all (100%) patients. Uveitis and nephritis were diagnosed within 1 week from each other. Although two showed recurrences, the topical and systemic steroid treatment with mean duration of 14.1 months brought the resolution of nephritis and uveitis in all patients. Recurrence-free periods ranged from 12 to 71 months. The final visual outcome was 20/20 or better in all cases. HLA-DR4 or the allele of DRB1∗04 was present in all (100%) patients. Conclusions. TINU should be considered in the differential diagnosis in young patients with uveitis of unknown origin and renal dysfunction. Urinary β2 microglobulin level and HLA typing may help in the diagnosis of TINU. The prognosis for patients with TINU is generally good with steroid treatment.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

A comparison of two approaches to biofeedback treatment in children with recalcitrant constipation/encopresis. Long term follow up

2001 ◽  
Vol 120 (5) ◽  
pp. A397-A397
Author(s):  
M SAMERAMMAR ◽  
J CROFFIE ◽  
M PFEFFERKORN ◽  
S GUPTA ◽  
M CORKINS ◽  
...  
Keyword(s):  
Long Term Follow Up ◽  
Biofeedback Treatment

Endoscopic sphiecterotomy without cholecystectomy for prevention of recurrence of acute billary pancreatitis: Long-term follow-up of 73 patients

2001 ◽  
Vol 120 (5) ◽  
pp. A204-A204
Author(s):  
B GONZALEZCONDE ◽  
J VAZQUEZIGLESIAS ◽  
L LOPEZROSES ◽  
P ALONSOAGUIRRE ◽  
A LANCHO ◽  
...  
Keyword(s):  
Long Term Follow Up ◽  
Prevention Of Recurrence

Epidemilogical long term follow up in functional dyspepsia: Characteristics of non-responders

2001 ◽  
Vol 120 (5) ◽  
pp. A754-A755 ◽  
Author(s):  
H ALLESCHER ◽  
P ENCK ◽  
G ADLER ◽  
R DIETL ◽  
J HARTUNG ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Long Term Follow Up

8: Predictors of HRQOL Duirng Long-Term Follow-Up of Men Treated for Prostate Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 3-4
Author(s):  
George J. Huang ◽  
Natalia Sadetsky ◽  
Peter R. Carroll ◽  
David F. Penson
Keyword(s):  
Prostate Cancer ◽  
Long Term Follow Up

774: Long-Term Follow-Up of Children with Continent Cutaneous Urinary Diversion

2006 ◽  
Vol 175 (4S) ◽  
pp. 251-251
Author(s):  
Annette Schröder ◽  
Raimund Stein ◽  
Rolf Beetz ◽  
Joachim W. Thüroff
Keyword(s):  
Urinary Diversion ◽  
Long Term Follow Up ◽  
Continent Cutaneous Urinary Diversion
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