RAPID AND SENSITIVE SIMULTANEOUS ESTIMATION OF METFORMIN HYDROCHLORIDE AND PIOGLITAZONE HYDROCHLORIDE IN TABLET FORMULATION BY HPTLC METHOD

2013 ◽  
Vol 36 (5) ◽  
pp. 618-627 ◽  
Author(s):  
Darshana K. Modi ◽  
Bhavesh H. Patel
Keyword(s):  
Tablet Formulation ◽  
Metformin Hydrochloride ◽  
Simultaneous Estimation ◽  
Hptlc Method

DEVELOPMENT OF HPTLC METHOD FOR SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN AND ORNIDAZOLE IN COMBINED DOSAGE FORM

INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (05) ◽  
pp. 36-43
Author(s):  
N. R Dighade ◽  
◽  
M. D Shende ◽  
A. V Kasture
Keyword(s):  
Quality Control ◽  
High Resolution ◽  
Thin Layer ◽  
Mobile Phase ◽  
High Performance ◽  
Dosage Form ◽  
Simultaneous Estimation ◽  
Ich Guidelines ◽  
Hptlc Method ◽  
Routine Quality Control

A simple and accurate high performance thin layer chromatographic (HPLTC) method has been developed and validated as per ICH guidelines for estimations of Ciprofloxacin (CP) and Ornidazole (ORN) in combined dosage form. The mobile phase was acetonitrile: toluene: water and triethylamine (5.5:1.8:1.5:1.6 V/V) was found to be best which gave high resolution with Rf 0.16 and 0.84 for ciprofloxacin and ornidazole respectively. The linearity of ciprofloxacin and ornidazole was found to be in the range of 0.4 to 0.8 µg/mL and 0.4 to 0.8 µg/mL, respectively. The coefficient of correlation (r2 ) was found to be greater than 0.989 for both the components by this method. The tablet analyses result (n = 5) were found to be > 100.84 % by HPTLC for both the components. The proposed method was found to be simple, accurate and suitable for routine quality control of marketed formulations containing these drugs.

Development and validation of an HPTLC method for simultaneous estimation of thiocolchicoside and aceclofenac in combined dosage form

2012 ◽  
Vol 25 (2) ◽  
pp. 133-137 ◽  
Author(s):  
Pratima Syal ◽  
Madhusmita Sahoo ◽  
Rahul Raut ◽  
Asawaree Hable ◽  
Amruta Battewar ◽  
...  
Keyword(s):  
Dosage Form ◽  
Simultaneous Estimation ◽  
Development And Validation ◽  
Hptlc Method

Development and validation of HPTLC method for the estimation of desvenlafaxine in tablet formulation

2012 ◽  
Vol 25 (2) ◽  
pp. 174-177
Author(s):  
Dimal Shah ◽  
Riddhi Nakrani ◽  
Sunil Baldania ◽  
Usmangani Chhalotiya ◽  
Kashyap Bhatt
Keyword(s):  
Tablet Formulation ◽  
Development And Validation ◽  
Hptlc Method
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