Synthesis, structural characterization, in vitro DNA binding, and antitumor activity properties of Ru(II) compounds containing 2(2,6-dimethoxypyridine-3-yl)-1H-imidazo(4,5-f)[1, 10]phenanthroline

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Nagamani Chintakuntla ◽  
Venkat Reddy Putta ◽  
Rajender Reddy Mallepally ◽  
Nagasuryaprasad K ◽  
Ravi Kumar Vuradi ◽  
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Cytotoxicity, DNA binding and cell apoptosis induction of a zinc(ii) complex of HBrQ

MedChemComm ◽  
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Hai-Rong Zhang ◽  
Yan-Cheng Liu ◽  
Ting Meng ◽  
Qi-Pin Qin ◽  
Shang-Feng Tang ◽  
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Dna Binding ◽  
Antitumor Activity ◽  
Cell Apoptosis ◽  
Antitumor Effect ◽  
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Mitochondria Dysfunction ◽  
Phase Arrest ◽  
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A zinc(ii) complex of HBrQ showed higher in vitro antitumor activity. It induced cell apoptosis in BEL-7404 cells via G2 phase arrest, led to mitochondria dysfunction and activation of caspase cascade. The central zinc(ii) should play a key role to enhance the antitumor effect

Synthesis, structural characterization, and in vitro antitumor activity of novel N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)arylsulfonamides

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pp. 2560-2572 ◽  
Author(s):  
Zdzisław Brzozowski ◽  
Franciszek Sączewski ◽  
Jarosław Sławiński ◽  
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Chunyan Yan ◽  
Yin Yin ◽  
Dawei Zhang ◽  
Wei Yang ◽  
Rongmin Yu
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Antitumor Activity ◽  
Structural Characterization ◽  
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RSC Advances ◽  
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Author(s):  
Yongjie Wang ◽  
Xinquan Liu ◽  
Jiaozhen Zhang ◽  
Guangpu Liu ◽  
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Vol 213 ◽  
pp. 361-369 ◽  
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Liang Yan ◽  
Chuan Xiong ◽  
Pan Xu ◽  
Jing Zhu ◽  
Zhirong Yang ◽  
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Antitumor Activity ◽  
Structural Characterization ◽  
Artemisia Annua ◽  
Artemisia Annua L
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