Investigation of 1,3-Dipolar Cycloaddition Reactions of Unsaturated Nitrones in Ionic Liquids

2006 ◽  
Vol 25 (8) ◽  
pp. 867-870 ◽  
Author(s):  
M. Hornyák ◽  
Z. Kele ◽  
L. Kovács ◽  
P. Forgó ◽  
N. M. Howarth
Keyword(s):  
Ionic Liquids ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions

scholarly journals Recent Developments on 1,3-Dipolar Cycloaddition Reactions by Catalysis in Green Solvents

Catalysts ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 65 ◽  
Author(s):  
Loredana Maiuolo ◽  
Vincenzo Algieri ◽  
Fabrizio Olivito ◽  
Antonio De Nino
Keyword(s):  
Ionic Liquids ◽  
Heterocyclic Compounds ◽  
Deep Eutectic Solvents ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Important Class ◽  
Green Solvents ◽  
Dipolar Cycloadditions ◽  
Recent Developments ◽  
Selection Of

The use of eco-compatible synthetic procedures in organic reactions and, in particular, in 1,3-dipolar cycloaddition reactions, has recently received a great deal of attention and considerable progress has been achieved in this area in the last years. This review summarizes the approaches currently employed to synthesize heterocyclic compounds by catalyzed 1,3-dipolar cycloadditions in green solvents in the last six years. Our choice to do a selection of the literature from 2014 to 2019 was made considering the absence of a recent review about this period, to our knowledge. Several examples to construct heterocycles by 1,3-dipolar cycloadditions will be discussed in this work subdivided in function of the most important class of non-conventional and green solvents, i.e., ionic liquids (ILs), deep eutectic solvents (DES), and water.

Rate accelerations of 1,3-dipolar cycloaddition reactions in ionic liquids

2000 ◽  
Vol 41 (38) ◽  
pp. 7351-7355 ◽  
Author(s):  
Joan Fraga Dubreuil ◽  
Jean Pierre Bazureau
Keyword(s):  
Ionic Liquids ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions

Multicomponent 1,3-Dipolar Cycloaddition Reactions in the Construction of Hybrid Spiroheterocycles

2013 ◽  
Vol 17 (18) ◽  
pp. 1929-1956 ◽  
Author(s):  
Natarajan Arumugam ◽  
Raju Kumar ◽  
Abdulrahman Almansour ◽  
Subbu Perumal
Keyword(s):  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions

π-Facial Selectivity in 1,3-Dipolar Cycloaddition Reactions of α-Methylidene-γ-lactone Substituted by 4-Methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl Group in γ-Position

2002 ◽  
Vol 67 (3) ◽  
pp. 353-364 ◽  
Author(s):  
Petr Melša ◽  
Ctibor Mazal
Keyword(s):  
Double Bond ◽  
Carboxylic Acid ◽  
Nitrile Oxide ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Enantiomerically Pure ◽  
Nitrile Imine ◽  
Facial Selectivity ◽  
Excellent Selectivity

Diastereoselectivity of 1,3-dipolar cycloaddition reactions of benzyl azide, diazomethane, a nitrile oxide and a nitrile imine to α-methylidene-γ-lactone dipolarophile was effectively controlled by a bulky γ-substituent, 4-methyl-2,6,7-trioxabicyclo[2.2.2]octan-1-yl in γ-position of the dipolarophile. The dipoles added from the less hindered face of the double bond with an excellent selectivity. Enantiomerically pure dipolarophile was prepared from the easily available (S)-5-oxotetrahydrohydrofuran-2-carboxylic acid.

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