Natural and Synthetic Polymers as Drug Carriers for Delivery of Therapeutic Proteins

2015 ◽  
Vol 55 (3) ◽  
pp. 371-406 ◽  
Author(s):  
Muhammad Sajid Hamid Akash ◽  
Kanwal Rehman ◽  
Shuqing Chen
Chemistry ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 164-181
Author(s):  
Joyita Sarkar ◽  
Swapnil C. Kamble ◽  
Nilambari C. Kashikar

Three-dimensional (3D) printing techniques have revolutionized the field of tissue engineering. This is especially favorable to construct intricate tissues such as liver, as 3D printing allows for the precise delivery of biomaterials, cells and bioactive molecules in complex geometries. Bioinks made of polymers, of both natural and synthetic origin, have been very beneficial to printing soft tissues such as liver. Using polymeric bioinks, 3D hepatic structures are printed with or without cells and biomolecules, and have been used for different tissue engineering applications. In this review, with the introduction to basic 3D printing techniques, we discuss different natural and synthetic polymers including decellularized matrices that have been employed for the 3D bioprinting of hepatic structures. Finally, we focus on recent advances in polymeric bioinks for 3D hepatic printing and their applications. The studies indicate that much work has been devoted to improvising the design, stability and longevity of the printed structures. Others focus on the printing of tissue engineered hepatic structures for applications in drug screening, regenerative medicine and disease models. More attention must now be diverted to developing personalized structures and stem cell differentiation to hepatic lineage.


1993 ◽  
Vol 20 (3) ◽  
pp. 257-274 ◽  
Author(s):  
Tokio Morikawa ◽  
Eiji Yanai ◽  
Takeo Okada ◽  
Teiichi Watanabe ◽  
Yoshinobu Sato

2010 ◽  
Vol 17 (2-3) ◽  
pp. 239-245 ◽  
Author(s):  
D. Geetha ◽  
M. Prakash ◽  
P. S. Ramesh ◽  
C. Rakkappan

Biomaterials ◽  
1998 ◽  
Vol 19 (1-3) ◽  
pp. 147-155 ◽  
Author(s):  
S. Dutoya ◽  
F. Lefebvre ◽  
C. Deminières ◽  
F. Rouais ◽  
A. Verna ◽  
...  

2014 ◽  
Vol 463 (2) ◽  
pp. 127-136 ◽  
Author(s):  
George Dan Mogoşanu ◽  
Alexandru Mihai Grumezescu

2020 ◽  
Vol 4 (4) ◽  
pp. 175
Author(s):  
Dorel Feldman

Poly(vinyl alcohol) (PVA) is a thermoplastic synthetic polymer, which, unlike many synthetic polymers, is not obtained by polymerization, but by hydrolysis of poly(vinyl acetate) (PVAc). Due to the presence of hydroxylic groups, hydrophilic polymers such as PVA and its composites made mainly with biopolymers are used for producing hydrogels that possess interesting morphological and physico-mechanical features. PVA hydrogels and other PVA composites are studied in light of their numerous application for electrical film membranes for chemical separation, element and dye removal, adsorption of metal ions, fuel cells, and packaging. Aside from applications in the engineering field, PVA, like other synthetic polymers, has applications in medicine and biological areas and has become one of the principal objectives of the researchers in the polymer domain. The review presents a few recent applications of PVA composites and contributions related to tissue engineering (repair and regeneration), drug carriers, and wound healing.


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