A retrospective review of the management of an abnormal fetal blood sample in primigravidae patients treated with oxytocin in labour

2003 ◽  
Vol 23 (sup1) ◽  
pp. S67-S67
Author(s):  
T. Walsh ◽  
M. O'Connell ◽  
M. O'Leary ◽  
Catherine Mcquillan ◽  
C. O'Herlhy ◽  
...  
Keyword(s):  
Blood Sample ◽  
Retrospective Review ◽  
Fetal Blood ◽  
Fetal Blood Sample

Trisomy 12 mosaicism in amniocytes and dysmorphic child despite normal chromosomes in fetal blood sample

1989 ◽  
Vol 9 (6) ◽  
pp. 433-437 ◽  
Author(s):  
Harriet von Koskull ◽  
Annukka Ritvanen ◽  
Pirkko Ämmälä ◽  
Nina Gahmberg ◽  
Riitta Salonen
Keyword(s):  
Blood Sample ◽  
Fetal Blood ◽  
Trisomy 12 ◽  
Fetal Blood Sample

RETROSPECTIVE REVIEW: The Varieties in Historical and Contemporary Contexts

1987 ◽  
Vol 32 (9) ◽  
pp. 773-778 ◽  
Author(s):  
Richard L. Gorsuch ◽  
Bernard Spilka
Keyword(s):  
Retrospective Review

A Simple and Rapid Method to Determine GPIIb/IIIa-Receptor Inhibitor Activity in Whole Blood

1999 ◽  
Vol 19 (03) ◽  
pp. 134-138
Author(s):  
Gitta Kühnel ◽  
A. C. Matzdorff
Keyword(s):  
Flow Cytometry ◽  
Platelet Count ◽  
Blood Sample ◽  
Platelet Activation ◽  
Whole Blood ◽  
Receptor Occupancy ◽  
Aggregate Formation ◽  
Inhibitor Activity ◽  
Receptor Inhibitor

SummaryWe studied the effect of GPIIb/IIIa-inhibitors on platelet activation with flow cytometry in vitro. Citrated whole blood was incubated with increasing concentrations of three different GPIIb/IIIa-inhibitors (c7E3, DMP728, XJ757), then thrombin or ADP were added and after 1 min the sample was fixed. Samples without c7E3 but with 0.1 U/ml thrombin had a decrease in platelet count. Samples with increasing concentrations of c7E3 had a lesser or no decrease in platelet count. The two other inhibitors (DMP 725, XJ757) gave similar results. GPIIb/IIIa-inhibitors prevent aggregate formation and more single platelets remain in the blood sample. The agonist-induced decrease in platelet count correlates closely with the concentration of the GPIIb/IIIa inhibitor and receptor occupancy. This correlation may be used as a simple measure for inhibitor activity in whole blood.

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