Postoperative infections and antibiotic prophylaxis for hysterectomy in Sweden: a study by the Swedish National Register for Gynecologic Surgery

2004 ◽  
Vol 83 (12) ◽  
pp. 1202-1207 ◽  
Author(s):  
Mats Löfgren ◽  
Inger Sundström Poromaa ◽  
Jan Henrik Stjerndahl ◽  
Birgitta Renström
Keyword(s):  
Antibiotic Prophylaxis ◽  
Gynecologic Surgery ◽  
Postoperative Infections ◽  
National Register

scholarly journals The A2B trial, antibiotic prophylaxis for excision-graft surgery in burn patients: a multicenter randomized double-blind study

Trials ◽  
2020 ◽  
Vol 21 (1) ◽  
Author(s):  
François Dépret ◽  
◽  
Boris Farny ◽  
Mathieu Jeanne ◽  
Kada Klouche ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Controlled Study ◽  
Control Group ◽  
Placebo Control ◽  
Double Blind Study ◽  
Burn Patients ◽  
Site Infection ◽  
Postoperative Sepsis ◽  
Postoperative Infections

Abstract Background The indication for antibiotic prophylaxis in burn patients remains highly controversial, with no consensus having been reached. The objective of antibiotic prophylaxis is to reduce the risk of postoperative local and systemic infections. Burn surgery is associated with a high incidence of bacteremia, postoperative infections, and sepsis. However, antibiotic prophylaxis exposes patients to the risk of selecting drug-resistant pathogens as well as to the adverse effects of antibiotics (i.e., Clostridium difficile colitis). The lack of data precludes any strong international recommendations regarding perioperative prophylaxis using systemic antibiotics in this setting. The goal of this project is therefore to determine whether perioperative systemic antibiotic prophylaxis can reduce the incidence of postoperative infections in burn patients. Methods The A2B trial is a multicenter (10 centers), prospective, randomized, double-blinded, placebo-controlled study. The trial will involve the recruitment of 506 adult burn patients with a total body surface area (TBSA) burn of between 5 and 40% and requiring at least one excision-graft surgery for deep burn injury. Participants will be randomized to receive antibiotic prophylaxis (antibiotic prophylaxis group) or a placebo (control group) 30 min before the incision of the first two surgeries. The primary outcome will be the occurrence of postoperative infections defined as postoperative sepsis and/or surgical site infection and/or graft lysis requiring a new graft within 7 days after surgery. Secondary outcomes will include mortality at day 90 postrandomization, skin graft lysis requiring a new graft procedure, postoperative bacteremia (within 48 h of surgery), postoperative sepsis, postoperative surgical site infection, number of hospitalizations until complete healing (> 95% TBSA), number of hospitalization days living without antibiotic therapy at day 28 and day 90, and multiresistant bacterial colonization or infection at day 28 and day 90. Discussion The trial aims to provide evidence on the efficacy and safety of antibiotic prophylaxis for excision-graft surgery in burn patients. Trial registration ClinicalTrials.gov NCT04292054. Registered on 2 March 2020

Surveillance for Postoperative Infections in Outpatient Gynecologic Surgery

1986 ◽  
Vol 7 (2) ◽  
pp. 54-58 ◽  
Author(s):  
James M. Garvey ◽  
Carol Buffenmyer ◽  
Russel Rule Rycheck ◽  
Robert Yee ◽  
Joanne McVay ◽  
...  
Keyword(s):  
Operating Room ◽  
Surgical Procedures ◽  
Surveillance System ◽  
Gynecologic Surgery ◽  
Computer Assisted ◽  
Postoperative Infections ◽  
Infection Surveillance ◽  
Life Threatening ◽  
The Difference ◽  
Clean Contaminated

AbstractPostoperative infection rates were determined for gynecologic outpatient surgical procedures performed in a traditional operating room environment and a separate, recently opened, surgicenter within the same hospital. Infections were self-reported by attending surgeons responding to computer-generated line listings of their recent surgical procedures. Responses were obtained on 97.9% (612/625) of women having surgery in the operating room and 99.5% (629/632) of women with surgicenter procedures. The overall infection rate for reported women was 0.9% (11/1,241). The difference between operating room and surgicenter rates was not statistically significant. Postoperative infections occurred in 2.5% (3/118) of diagnostic laparoscopies with tubal lavage and 1.4% (3/214) of voluntary abortions by dilatation and evacuation and curettage (D&E&C). The five other infections were scattered among the remaining 25 procedure categories. Ten of the 11 infections were limited to the “clean-contaminated” wounds. No serious or life-threatening infections were encountered. The computer-assisted surveillance system worked well and was easily incorporated into the existing infection surveillance system. The degree of ascertainment of postoperative wound infections is unknown due to reliance on physician self-reporting. However, no patients requiring readmission for infection went unreported by the attending surgeons.

Modifying pre-operative antibiotic overuse in gynecologic surgery

2018 ◽  
Vol 31 (5) ◽  
pp. 400-405 ◽  
Author(s):  
Robert Shapiro ◽  
Rose Laignel ◽  
Caitlin Kowcheck ◽  
Valerie White ◽  
Mahreen Hashmi
Keyword(s):  
Antibiotic Prophylaxis ◽  
Tertiary Care ◽  
Retrospective Chart Review ◽  
Secondary Outcome ◽  
Gynecologic Surgery ◽  
Content Type ◽  
Antibiotic Overuse ◽  
Perioperative Antibiotic Prophylaxis ◽  
System A ◽  
Before And After

Purpose Previous studies indicate adherence to pre-operative antibiotic prophylaxis guidelines has been inadequate. The purpose of this paper is to determine adherence rates to current perioperative antibiotic prophylaxis guidelines in gynecologic surgery at a tertiary care, academic institution. As a secondary outcome, improving guidelines after physician re-education were analyzed. Design/methodology/approach A retrospective chart review (2,463 patients) was completed. The authors determined if patients received perioperative antibiotic prophylaxis in accordance with current guidelines from the America College of Obstetricians and Gynecologists. Data were obtained before and after physician tutorials. Quality control was implemented by making guideline failures transparent. Statistical analysis used Fisher’s exact and agreement tests. Findings In total, 23 percent of patients received antibiotics not indicated across all procedures. This decreased to 9 percent after physician re-education and outcome transparency (p<0.0001). Laparoscopy was the procedure with the lowest guideline compliance prior to education. The compliance improved from 52 to 92 percent (p<0.0001) after re-education. Practical implications Gynecologic surgeons overuse antibiotics for surgical prophylaxis. Physician re-education and transparency were shown to enhance compliance. Originality/value Educational tutorials are an effective strategy for encouraging physicians to improve outcomes, which, in turn, allows the healthcare system a non-punitive way to monitor quality and mitigate cost.

scholarly journals Use of Guideline-Based Antibiotic Prophylaxis in Women Undergoing Gynecologic Surgery

2013 ◽  
Vol 122 (6) ◽  
pp. 1145-1153 ◽  
Author(s):  
Jason D. Wright ◽  
Khalid Hassan ◽  
Cande V. Ananth ◽  
Thomas J. Herzog ◽  
Sharyn N. Lewin ◽  
...  
Keyword(s):  
Antibiotic Prophylaxis ◽  
Gynecologic Surgery

scholarly journals Mucogingival Abscess Following Implant Surgery

2018 ◽  
Vol 2 (3) ◽  
pp. 527-530
Author(s):  
Ronald Garrido
Keyword(s):  
Antibiotic Therapy ◽  
Antibiotic Prophylaxis ◽  
Antibiotic Treatment ◽  
Bacterial Contamination ◽  
Recommended Dose ◽  
Postoperative Infections ◽  
Implant Surgery

The rehabilitation of lost teeth, by means of implants has grown exponentially and thus the use of antibiotic therapy to prevent postoperative infectious pictures. The use of antibiotics has proved beneficial avoiding the failure of a large number of implants from bacterial contamination , in comparison to non-use of these . Although the use of antibiotic prophylaxis or treatment is controversial , studies suggest that antibiotic prophylaxis is more effective than antibiotic treatment in preventing postoperative infections, being 2g amoxicillin one hour before the recommended dose.

scholarly journals The Effect of Short v.s Long -Term Antibiotic Prophylaxis in Gynecologic Surgery

2021 ◽  
Vol 26 (4) ◽  
pp. 526-532
Author(s):  
Ecem Kaya ◽  
Onur Kaya ◽  
Cemre Celik ◽  
Cem Dane
Keyword(s):  
Antibiotic Prophylaxis ◽  
Gynecologic Surgery
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