Metachromatic leukodystrophy: Diffusion MR imaging and proton MR spectroscopy
2003 ◽
Vol 44
(4)
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pp. 440-443
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Keyword(s):
Metachromatic leukodystrophy is characterized by dysmyelination caused by a deficiency of arylsulfatase-A. In a 17-month-old boy with metachromatic leukodystrophy, an echo-planar diffusion MR sequence revealed a restricted diffusion pattern in the deep white matter, manifested by high-signal on b = 1000 s/mm2 images, and low ADC values (0.56 × 10−3 mm2/s). Proton MR spectroscopy revealed a marked decrease in choline, a metabolite related to myelin turnover. These observations consisting of a restricted diffusion pattern on diffusion MR imaging, and decreased choline peaks on proton spectroscopy, likely represented dysmyelination in metachromatic leukodystrophy.
2003 ◽
Vol 44
(4)
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pp. 440-443
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Keyword(s):
2007 ◽
Vol 28
(7)
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pp. 1332-1338
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Keyword(s):
2020 ◽
Vol 21
(3)
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pp. 1020
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Keyword(s):
2004 ◽
Vol 31
(2)
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pp. 138-141
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2006 ◽
Vol 33
(3)
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pp. 207-208
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Keyword(s):
2012 ◽
Vol 81
(12)
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pp. 4057-4063
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Keyword(s):
2004 ◽
Vol 31
(3)
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pp. 238-240
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Keyword(s):