Diffusion-weighted imaging in hyperacute stroke – gold standard?

2003 ◽  
Vol 44 (5) ◽  
pp. 547-549 ◽  
Author(s):  
Y.-Y. Wong ◽  
W. W.-M. Lam

Diffusion-weighted imaging (DWI) is more sensitive than CT and conventional T2-weighted MR imaging in the detection of early cerebral ischemia and infarction. In this case report, we present a case of a 79-year-old woman with symptoms of acute stroke, clinically and radiologically documented progression to complete stroke with an initial negative diffusion-weighted scan.

1998 ◽  
Vol 39 (5) ◽  
pp. 460-473 ◽  
Author(s):  
T. Q. Li ◽  
Z. G. Chen ◽  
T. Hindmarsh

Diffusion-weighted MR imaging has been used in studies on experimental animal models and on patients with acute cerebral ischemia. Compared with CT and conventional MR techniques, diffusion-weighted imaging can provide earlier and more precise detection of the location and the extent of an ischemic lesion during the critical first few hours after the onset of stroke Quantitative apparent diffusion coefficient (ADC) mapping of the brain water can also be carried out by recording a series of diffusion-weighted images with different amplitudes of the displacement encoding gradients. ADC maps can provide important information about the extra- and intracellular water homeostasis. ADC reduction of the tissue water is one of the early signals of the pathophysiological cascade resulting from ischemic tissue injury. Diffusion MR imaging has become a valuable tool in stroke research. It may also prove a valuable tool in monitoring the efficiency of therapeutic effects in stroke patients It is our intention to provide an overview of the recent development in this area with emphasis on the diffusion-weighted MR techniques, and to discuss the possible underlying biophysical mechanisms responsible for the contrast of diffusion-weighted imaging


Nosotchu ◽  
2006 ◽  
Vol 28 (2) ◽  
pp. 280-285 ◽  
Author(s):  
Tatsuya Ishikawa ◽  
Naoki Yuasa ◽  
Takashi Otomo ◽  
Hideki Shiramizu ◽  
Hiroshi Matsuda ◽  
...  

2009 ◽  
Vol 27 (6) ◽  
pp. 616-617 ◽  
Author(s):  
Aidos Doskaliyev ◽  
Fumiyuki Yamasaki ◽  
Taiichi Saito ◽  
Eiichi Nomura ◽  
Kazuhiko Sugiyama ◽  
...  

2017 ◽  
Vol 21 (1) ◽  
Author(s):  
Zeynep Cetiner-Alpay ◽  
Fatma Kulali ◽  
Aslihan Semiz-Oysu ◽  
Yasar Bukte ◽  
Kamil Ozdil

Background: Although endoscopic retrograde cholangiopancreatography (ERCP) is accepted as the gold standard, there is a place for magnetic resonance cholangiopancreatography (MRCP) and diffusion-weighted imaging (DWI) in the diagnosis of obstructive biliary disorders.Aim: To compare the findings of MRCP with ERCP in patients with obstructive biliary disorders and to investigate the diagnostic efficacy of MRCP combined with DWI.Study design: Retrospective, analytic, cross-sectional study.Methods: The MRCP images of 126 patients who underwent both MRCP and ERCP owing to biliary obstruction were reviewed. Nine patients were excluded because of incomplete diagnostic workup or a long period (>3 months) between MRCP and ERCP. Ninety-two patients underwent DWI, which was also evaluated. The sensitivity, specificity and accuracy of MRCP and DWI were analysed.Results: The sensitivity, specificity and accuracy of MRCP according to ERCP results as the gold standard was 97%, 71% and 93% for assessment of biliary dilatation; 100%, 94.7% and 97.5% for the diagnosis of choledocholithiasis; 93.7%, 100% and 99% for the identification of benign strictures; 100%, 100% and 100% for the diagnosis of malignant tumours; and 100%, 100% and 100% for the detection of complicated hydatid cysts; respectively. The sensitivity and specificity of DWI for the diagnosis of malignant tumour was 100%. In the detection of choledocholithiasis, the sensitivity and specificity of DWI was 70.8% and 100%.Conclusions: MRCP is an alternative, non-invasive, diagnostic modality, comparable with ERCP for the evaluation of pancreaticobiliary diseases. DWI can be helpful for diagnosis of choledocholithiasis and tumours.


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