scholarly journals Thrombocytopenia in a Mouse Model of Human Granulocytic Ehrlichiosis

2001 ◽  
Vol 184 (11) ◽  
pp. 1475-1479 ◽  
Author(s):  
Dori L. Borjesson ◽  
Scott I. Simon ◽  
Fern Tablin ◽  
Stephen W. Barthold
1999 ◽  
Vol 37 (6) ◽  
pp. 2077-2079 ◽  
Author(s):  
Joseph E. Bunnell ◽  
Louis A. Magnarelli ◽  
J. Stephen Dumler

Laboratory diagnosis of Borrelia burgdorferi is routinely made by an enzyme-linked immunosorbent assay, with positive results confirmed by Western blot analysis. Concern has been raised that false-positive diagnoses may be made on the basis of serologic cross-reactivity with antibodies directed against other bacterial pathogens, in particular the agent of human granulocytic ehrlichiosis (HGE). The present study made use of a mouse model to ascertain the validity of these concerns. Two different strains of mice were inoculated with the HGE agent and assayed for production of polyclonal and monoclonal antibodies to antigens of both of these bacteria. Infection of mice with the HGE agent does not induce diagnostically significant B. burgdorferi serologic cross-reactions.


Infection ◽  
2001 ◽  
Vol 29 (5) ◽  
pp. 271-273 ◽  
Author(s):  
R. Woessner ◽  
B.C. Gaertner ◽  
M.T. Grauer ◽  
K. Weber ◽  
N. Mueller-Lantzsch ◽  
...  

1998 ◽  
Vol 27 (6) ◽  
pp. 1424-1427 ◽  
Author(s):  
Arshad Jahangir ◽  
Chris Kolbert ◽  
William Edwards ◽  
Paul Mitchell ◽  
J. Stephen Dumler ◽  
...  

2003 ◽  
Vol 9 (11) ◽  
pp. 1499-1500 ◽  
Author(s):  
Tiina Prükk ◽  
Kylliki Ainsalu ◽  
Ene Laja ◽  
Ada Aigro

1997 ◽  
Vol 107 (2) ◽  
pp. 142-147 ◽  
Author(s):  
Gary P. Wormser ◽  
Harold W. Horowitz ◽  
John Nowakowski ◽  
Donna Mckenna ◽  
J. Stephen Dumler ◽  
...  

2003 ◽  
Vol 47 (2) ◽  
pp. 129-132 ◽  
Author(s):  
P. Heyman ◽  
C. Cochez ◽  
G. Bigaignon ◽  
B. Guillaume ◽  
M. Zizi ◽  
...  

2001 ◽  
Vol 32 (6) ◽  
pp. 862-870 ◽  
Author(s):  
J. S. Bakken ◽  
M. E. Aguero-Rosenfeld ◽  
R. L. Tilden ◽  
G. P. Wormser ◽  
H. W. Horowitz ◽  
...  

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