The FLUKA Monte Carlo code coupled with the local effect model for biological calculations in carbon ion therapy

2010 ◽  
Vol 55 (15) ◽  
pp. 4273-4289 ◽  
Author(s):  
A Mairani ◽  
S Brons ◽  
F Cerutti ◽  
A Fassò ◽  
A Ferrari ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Local Effect ◽  
Monte Carlo Code ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Effect Model ◽  
Ion Therapy

The FLUKA Monte Carlo code coupled with the NIRS approach for clinical dose calculations in carbon ion therapy

2017 ◽  
Vol 62 (9) ◽  
pp. 3814-3827 ◽  
Author(s):  
G Magro ◽  
T J Dahle ◽  
S Molinelli ◽  
M Ciocca ◽  
P Fossati ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Code ◽  
Dose Calculations ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Clinical Dose ◽  
Ion Therapy

Distributions of secondary particles in proton and carbon-ion therapy: a comparison between GATE/Geant4 and FLUKA Monte Carlo codes

2013 ◽  
Vol 58 (9) ◽  
pp. 2879-2899 ◽  
Author(s):  
C Robert ◽  
G Dedes ◽  
G Battistoni ◽  
T T Böhlen ◽  
I Buvat ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Secondary Particles ◽  
Ion Therapy

SU-E-T-499: Initial Developments of An OpenCL-Based Cross-Platform Monte Carlo Dose Engine for Carbon Ion Therapy

2015 ◽  
Vol 42 (6Part20) ◽  
pp. 3449-3449 ◽  
Author(s):  
N Qin ◽  
M Pinto ◽  
Z Tian ◽  
G Dedes ◽  
A Pompos ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Ion Therapy ◽  
Cross Platform

The influence of lateral beam profile modifications in scanned proton and carbon ion therapy: a Monte Carlo study

2010 ◽  
Vol 55 (17) ◽  
pp. 5169-5187 ◽  
Author(s):  
K Parodi ◽  
A Mairani ◽  
S Brons ◽  
J Naumann ◽  
M Krämer ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Study ◽  
Beam Profile ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Ion Therapy

scholarly journals Initial development of goCMC: a GPU-oriented fast cross-platform Monte Carlo engine for carbon ion therapy

2017 ◽  
Vol 62 (9) ◽  
pp. 3682-3699 ◽  
Author(s):  
Nan Qin ◽  
Marco Pinto ◽  
Zhen Tian ◽  
Georgios Dedes ◽  
Arnold Pompos ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Initial Development ◽  
Carbon Ion Therapy ◽  
Carbon Ion ◽  
Ion Therapy ◽  
Cross Platform

scholarly journals Carbon Ion Dose Constraints in the Head and Neck and Skull Base: Review of MedAustron Institutional Protocols

2021 ◽  
Vol 8 (1) ◽  
pp. 25-35
Author(s):  
Piero Fossati ◽  
Ana Perpar ◽  
Markus Stock ◽  
Petra Georg ◽  
Antonio Carlino ◽  
...  
Keyword(s):  
Head And Neck ◽  
Local Effect ◽  
Brain Parenchyma ◽  
Carbon Ion Radiotherapy ◽  
Carbon Ion ◽  
Effect Model ◽  
Dose Volume ◽  
Ion Therapy ◽  
Dose Constraints ◽  
Fractionation Schedules

Abstract Background Dose constraints are of paramount importance for the outcome of any radiotherapy treatment. In this article, we report dose-volume constraints as well as currently used fractionation schedules for carbon ion radiotherapy as applied in MedAustron (Wiener Neustadt, Austria). Materials and Methods For fractionation schedules, both German and Japanese regimes were used. From the clinical experience of National Institute of Radiological Sciences (Chiba, Japan) and Heidelberg Ion Therapy (Heidelberg, Germany; formerly GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany) and the work by colleagues in Centro Nazionale Adroterapia Oncologica (Pavia, Italy) recalculating the dose from the microdosimetric kinetic model to the local effect model, we have set the dose constraints for critical organs of the head and neck area. Where no clinical data was available, an educated guess was made, based on data available from photon and proton series. Results We report the constraints for the optic nerve and chiasm, brainstem, spinal cord, cochlea, brain parenchyma, salivary gland, eye and adnexa, and mandibular/maxillary bone; constraints are grouped based on a fractionation scheme (German versus Japanese) and the risk of toxicity (safe, low to middle, and middle to high). Conclusion We think validation of dose constraints should present a relevant part of the activity of any carbon ion radiotherapy facility, and we anticipate future multicentric, joint evaluations.

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