An open-source framework for stress-testing non-invasive foetal ECG extraction algorithms

2016 ◽  
Vol 37 (5) ◽  
pp. 627-648 ◽  
Author(s):  
Fernando Andreotti ◽  
Joachim Behar ◽  
Sebastian Zaunseder ◽  
Julien Oster ◽  
Gari D Clifford
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mohammadreza Yaghoobi ◽  
Krzysztof S. Stopka ◽  
Aaditya Lakshmanan ◽  
Veera Sundararaghavan ◽  
John E. Allison ◽  
...  

AbstractThe PRISMS-Fatigue open-source framework for simulation-based analysis of microstructural influences on fatigue resistance for polycrystalline metals and alloys is presented here. The framework uses the crystal plasticity finite element method as its microstructure analysis tool and provides a highly efficient, scalable, flexible, and easy-to-use ICME community platform. The PRISMS-Fatigue framework is linked to different open-source software to instantiate microstructures, compute the material response, and assess fatigue indicator parameters. The performance of PRISMS-Fatigue is benchmarked against a similar framework implemented using ABAQUS. Results indicate that the multilevel parallelism scheme of PRISMS-Fatigue is more efficient and scalable than ABAQUS for large-scale fatigue simulations. The performance and flexibility of this framework is demonstrated with various examples that assess the driving force for fatigue crack formation of microstructures with different crystallographic textures, grain morphologies, and grain numbers, and under different multiaxial strain states, strain magnitudes, and boundary conditions.


2021 ◽  
Vol 11 (13) ◽  
pp. 6086
Author(s):  
Nils Ellendt ◽  
Fabian Fabricius ◽  
Anastasiya Toenjes

Additive manufacturing processes offer high geometric flexibility and allow the use of new alloy concepts due to high cooling rates. For each new material, parameter studies have to be performed to find process parameters that minimize microstructural defects such as pores or cracks. In this paper, we present a system developed in Python for accelerated image analysis of optical microscopy images. Batch processing can be used to quickly analyze large image sets with respect to pore size distribution, defect type, contribution of defect type to total porosity, and shape accuracy of printed samples. The open-source software is independent of the microscope used and is freely available for use. This framework allows us to perform such an analysis on a circular area with a diameter of 5 mm within 10 s, allowing detailed process maps to be obtained for new materials within minutes after preparation.


Author(s):  
Marco Langiu ◽  
David Yang Shu ◽  
Florian Joseph Baader ◽  
Dominik Hering ◽  
Uwe Bau ◽  
...  

2008 ◽  
Vol 24 (18) ◽  
pp. 2096-2097 ◽  
Author(s):  
R. C. G. Holland ◽  
T. A. Down ◽  
M. Pocock ◽  
A. Prlic ◽  
D. Huen ◽  
...  

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Agnes C Chlebinska ◽  
Sandeep Basavarajaiah ◽  
Ann O’Sullivan ◽  
Sanjay Sharma

Objectives: Sudden adult death syndrome (SADS) accounts for at least 4% of all sudden cardiac deaths in the United Kingdom and is often attributed to an ion channel disorder. The precise prevalence of and hence efficacy of effectiveness for screening for ion channel disorders utilising non-invasive cardiac tests in first degree relatives of victims of SADS is unknown. The aim of this study was to identify the prevalence of ion channel disorders in victims of SADS. Methods: Between March 2006 and March 2007, 17 families of victims of SADS were evaluated in a tertiary inherited cardiac clinic. A total of 46 individuals underwent 12-lead ECG, echocardiography, exercise stress testing, 24 hour Holter and, when applicable, an Ajmaline provocation test and/or cardiac magnetic resonance scan. Results: All family members had a structurally normal heart. An ion channel disorder was identified in 7 out of 17 (41%) families. Of these, 5 (71%) families exhibited the Brugada phenotype and 2 families manifested the long QT syndrome phenotype. A total of 11 of 46 (24%) asymptomatic family members were identified with an ion channel disorder. Conclusions: Non-invasive cardiac evaluation of first-degree family members of victims of SADS in a tertiary inherited cardiac diseases clinic suggests that ion channel disorders, particularly Brugada’s syndrome, account for at least 40% of all SADS deaths in the UK.


2021 ◽  
Author(s):  
Jason Anderson ◽  
Rami Beidas ◽  
Vimal Chacko ◽  
Hsuan Hsiao ◽  
Xiaoyi Ling ◽  
...  

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