scholarly journals Computer-aided Linear Algebra Course on Jupyter-Python Notebook for Engineering Undergraduates

2021 ◽  
Vol 1815 (1) ◽  
pp. 012004
Author(s):  
Chang Tang
Author(s):  
Ilzina Dmitrieva ◽  
Gennadiy Ivanov ◽  
Alexey Mineev

The need to improve the level of mathematical in particular geometric training of students of technical universities is due to modern technologies of computer-aided design. They are based on mathematical models of designed products, technological processes, etc., taking into account a large variety of source data. Therefore, from the first years of technical universities, when studying the cycle of mathematical disciplines, it is advisable to interpret a number of issues in terms and concepts of multidimensional geometry. At the same time, the combination of constructive (graphical) algorithms for solving problems in descriptive geometry with analytical algorithms in linear algebra and matanalysis allows us to summarize their advantages: the constructive approach provides the imagery inherent in engineering thinking, and the analytical approach provides the final result. The article shows the effectiveness of combining constructive and analytical algorithms for solving problems involving linear and nonlinear forms of many variables using specific examples.


Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.


Author(s):  
Greg V. Martin ◽  
Ann L. Hubbard

The microtubule (MT) cytoskeleton is necessary for many of the polarized functions of hepatocytes. Among the functions dependent on the MT-based cytoskeleton are polarized secretion of proteins, delivery of endocytosed material to lysosomes, and transcytosis of integral plasma membrane (PM) proteins. Although microtubules have been shown to be crucial to the establishment and maintenance of functional and structural polarization in the hepatocyte, little is known about the architecture of the hepatocyte MT cytoskeleton in vivo, particularly with regard to its relationship to PM domains and membranous organelles. Using an in situ extraction technique that preserves both microtubules and cellular membranes, we have developed a protocol for immunofluorescent co-localization of cytoskeletal elements and integral membrane proteins within 20 µm cryosections of fixed rat liver. Computer-aided 3D reconstruction of multi-spectral confocal microscope images was used to visualize the spatial relationships among the MT cytoskeleton, PM domains and intracellular organelles.


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