Diversity of HIV Type 1 and Drug Resistance Mutations Among Injecting Drug Users in Kenya

2013 ◽  
Vol 29 (1) ◽  
pp. 187-190 ◽  
Author(s):  
Saida Osman ◽  
Raphael W. Lihana ◽  
Rukia M. Kibaya ◽  
Azumi Ishizaki ◽  
Xiuqiong Bi ◽  
...  
2016 ◽  
Vol 06 (03) ◽  
pp. 111-115
Author(s):  
Anoumou Dagnra ◽  
Abla Konou ◽  
Mounerou Salou ◽  
Pascal Kodah ◽  
Damobé Kombate ◽  
...  

2011 ◽  
Vol 27 (7) ◽  
pp. 797-801 ◽  
Author(s):  
Jonathan Dean ◽  
Thu Hong Ta Thi ◽  
Linda Dunford ◽  
Michael J. Carr ◽  
Linh Thuy Nguyen ◽  
...  

2011 ◽  
Vol 27 (1) ◽  
pp. 71-80 ◽  
Author(s):  
B. Chaplin ◽  
G. Eisen ◽  
J. Idoko ◽  
D. Onwujekwe ◽  
E. Idigbe ◽  
...  

2008 ◽  
Vol 24 (9) ◽  
pp. 1133-1138 ◽  
Author(s):  
Maria Mercedes Santoro ◽  
Massimo Ciccozzi ◽  
Claudia Alteri ◽  
Stefania Montieri ◽  
Ivailo Alexiev ◽  
...  

2020 ◽  
Vol 18 (5) ◽  
pp. 362-372
Author(s):  
Chunyuan Huang ◽  
Li Ye ◽  
Abu S Abdullah ◽  
Bingyu Liang ◽  
Junjun Jiang ◽  
...  

Background: Whether HIV-positive injecting drug users (IDUs) are at higher risk of developing drug resistance mutations (DRMs) after methadone maintenance therapy (MMT) than any other HIV-positive population is unclear. Objective: To compare the incidence of new DRMs in two population groups: antiretroviraltreatment (ART) HIV-positive IDUs and non-drug users. Methods: A prospective cohort of ART HIV-positive patients including IDUs who received MMT (MMT group) and non-drug users (N-MMT group) was established from April 2016 to December 2017 in Guangxi, China. Results: Of the 80 participants, 43 were in the MMT group and 37 were in the N-MMT group. Compared with the N-MMT group, the HRs of PIs, NRTIs and NNRTIs for new DRMs in the MMT group was 1.55 (95%CI: 0.28-8.64; P = 0.616), 1.51 (95%CI: 0.44-5.20; P = 0.512) and 0.45 (95%CI: 0.15-1.35; P = 0.155), respectively. There was no dose-response relationship between MMT and new DRMs for PIs, NRTIs and NNRTIs (P > 0.05). The new DRM incidence for NRTIs (138.23 per 104 person-months) was higher than for PIs (94.16 per 104 person-months) and NNRTIs (95.41per 104 person-months) in the MMT group, while the new DRM incidence for NNRTIs (208.24 per 104 person-months) was higher than for PIs (44.13 per 104 person-months) and NRTIs (91.78 per 104 person-months) in the N-MMT group. Conclusion: Among ART HIV-positive patients, there is no significant difference in the incidence of new DRMs between IDUs receiving MMT and non-drug users. MMT has little impact on the development of DRMs among IDUs.


2012 ◽  
Vol 28 (8) ◽  
pp. 944-948 ◽  
Author(s):  
Hicham El Annaz ◽  
Patricia Recordon-Pinson ◽  
Rida Tagajdid ◽  
Toufik Doblali ◽  
Bouchra Belefquih ◽  
...  

2011 ◽  
Vol 27 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Lorena Martínez-Prats ◽  
Joanna Luczkowiak ◽  
Francisca Gutiérrez ◽  
Sagrario Zurita ◽  
Silvana Fiorante ◽  
...  

2012 ◽  
Vol 28 (9) ◽  
pp. 1157-1160 ◽  
Author(s):  
Marjorie Monleau ◽  
Avelin F. Aghokeng ◽  
Benedicte A. Nkano ◽  
Marie-Laure Chaix ◽  
Martine Peeters, and the AC11/AC12 ANRS Wor

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