Phase I/II Ex Vivo Gene Therapy Clinical Trial for Recessive Dystrophic Epidermolysis Bullosa Using Skin Equivalent Grafts Genetically Corrected with a COL7A1-Encoding SIN Retroviral Vector (GENEGRAFT)

Ex Vivo Gene Therapy ◽

Therapy Clinical Trial

Patient pre-selection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa.

10.26226/morressier.595a9c56d462b80296c9fadf ◽

2017 ◽

Author(s):

Su Lwin

Keyword(s):

Gene Therapy ◽

Phase I ◽

Epidermolysis Bullosa ◽

Ex Vivo ◽

Gene Therapy Trial ◽

Therapy Trial

EBGene trial: patient preselection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa

British Journal of Dermatology ◽

10.1111/bjd.18559 ◽

2019 ◽

Vol 182 (3) ◽

pp. 794-797 ◽

Cited By ~ 6

Author(s):

S. Gaucher ◽

S.M. Lwin ◽

M. Titeux ◽

A. Abdul‐Wahab ◽

N. Pironon ◽

...

Keyword(s):

Gene Therapy ◽

Phase I ◽

Epidermolysis Bullosa ◽

Ex Vivo ◽

Gene Therapy Trial ◽

Therapy Trial

SIN Retroviral Vectors Expressing COL7A1 Under Human Promoters for Ex Vivo Gene Therapy of Recessive Dystrophic Epidermolysis Bullosa

Molecular Therapy ◽

10.1038/mt.2010.91 ◽

2010 ◽

Vol 18 (8) ◽

pp. 1509-1518 ◽

Cited By ~ 72

Author(s):

Matthias Titeux ◽

Valérie Pendaries ◽

Maria A Zanta-Boussif ◽

Audrey Décha ◽

Nathalie Pironon ◽

...

Keyword(s):

Gene Therapy ◽

Epidermolysis Bullosa ◽

Ex Vivo ◽

Retroviral Vectors ◽

Ex Vivo Gene Therapy ◽

Faculty Opinions recommendation of SIN retroviral vectors expressing COL7A1 under human promoters for ex vivo gene therapy of recessive dystrophic epidermolysis bullosa.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718345163.793493591 ◽

2014 ◽

Author(s):

Jakub Tolar ◽

Michael Vanden Oever

Keyword(s):

Gene Therapy ◽

Epidermolysis Bullosa ◽

Ex Vivo ◽

Retroviral Vectors ◽

Ex Vivo Gene Therapy ◽

227 Patient pre-selection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa

10.1016/j.jid.2017.07.224 ◽

2017 ◽

Vol 137 (10) ◽

pp. S231

Author(s):

S.M. Lwin ◽

S. Gaucher ◽

M. Titeux ◽

A. Abdul-Wahab ◽

N. Pironon ◽

...

Keyword(s):

Gene Therapy ◽

Phase I ◽

Epidermolysis Bullosa ◽

Ex Vivo ◽

Gene Therapy Trial ◽

Therapy Trial

519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes

10.1016/j.jid.2017.02.539 ◽

2017 ◽

Vol 137 (5) ◽

pp. S89 ◽

Cited By ~ 2

Author(s):

Z. Siprashvili ◽

N. Nguyen ◽

E. Gorell ◽

K. Loutit ◽

Y. Dutt-Singkh ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Epidermolysis Bullosa ◽

367 Phase I clinical trial for Recessive Dystrophic Epidermolysis Bullosa using genetically corrected autologous keratinocytes

10.1016/j.jid.2016.02.400 ◽

2016 ◽

Vol 136 (5) ◽

pp. S65

Author(s):

Z. Siprashvili ◽

N.T. Nguyen ◽

E.S. Gorell ◽

K. Loutit ◽

P. Khuu ◽

...

Keyword(s):

Clinical Trial ◽

Phase I ◽

Epidermolysis Bullosa ◽

Phase I Clinical Trial ◽

Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent Grafts

Case Medical Research ◽

10.31525/ct1-nct04186650 ◽

2019 ◽

Author(s):

Keyword(s):

Clinical Trial ◽

Gene Therapy ◽

Ex Vivo ◽

Skin Equivalent ◽

Ex Vivo Gene Therapy ◽

Therapy Clinical Trial

155 Assessment of safety in repeat dosing of an in vivo topical gene therapy for the treatment of recessive dystrophic epidermolysis bullosa (RDEB) in a phase I/II trial

10.1016/j.jid.2021.02.175 ◽

2021 ◽

Vol 141 (5) ◽

pp. S28

Author(s):

M. Marinkovich ◽

S. Forte ◽

S. Oliver ◽

J. Dolorito ◽

K. Sridhar ◽

...

Keyword(s):

Gene Therapy ◽

Phase I ◽

Epidermolysis Bullosa ◽

Toward Epidermal Stem Cell-Mediated ex Vivo Gene Therapy of Junctional Epidermolysis Bullosa

Human Gene Therapy ◽

10.1089/104303400750035825 ◽

2000 ◽

Vol 11 (16) ◽

pp. 2283-2287 ◽

Cited By ~ 40

Author(s):

Elena Dellambra ◽

Graziella Pellegrini ◽

Liliana Guerra ◽

Giuliana Ferrari ◽

Giovanna Zambruno ◽

...

Keyword(s):

Gene Therapy ◽

Stem Cell ◽

Epidermolysis Bullosa ◽

Ex Vivo ◽

Epidermal Stem Cell ◽

Junctional Epidermolysis Bullosa ◽

Ex Vivo Gene Therapy