Trends in Salivary Gland Tissue Engineering: From Stem Cells to Secretome and Organoid Bioprinting

Author(s):  
Ajjima Chansaenroj ◽  
Supansa Yodmuang ◽  
João N. Ferreira
2015 ◽  
pp. 157-185 ◽  
Author(s):  
Daniel A. Harrington ◽  
Mariane Martinez ◽  
Danielle Wu ◽  
Swati Pradhan-Bhatt ◽  
Mary C. Farach-Carson

Author(s):  
Swati Pradhan-Bhatt ◽  
Kevin Cannon ◽  
Daniel Zakheim ◽  
Daniel A Harrington ◽  
Randall L Duncan ◽  
...  

2020 ◽  
Vol 15 (3) ◽  
pp. 1455-1461
Author(s):  
Erum Khan ◽  
Imran Farooq ◽  
Abdul Khabeer ◽  
Saqib Ali ◽  
Muhammad Sohail Zafar ◽  
...  

The salivary glands produce saliva, which helps in mediating the oral colonization of microbes, the repair of mucosa, the remineralization of teeth, lubrication and gustation. However, certain medications, therapeutic radiation and certain autoimmune diseases can cause a reduction in the salivary flow. The aim of this report was to review and highlight the indications and techniques of salivary gland engineering to counter hyposalivation. This report concludes that in the literature, numerous strategies have been suggested and discussed pertaining to the engineering of salivary gland, however, challenges remain in terms of its production and accurate function. Dedicated efforts are required from researchers all over the world to obtain the maximum benefits from salivary gland engineering techniques.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Chen Zhao ◽  
Cuida Meng ◽  
Na Cui ◽  
Jichao Sha ◽  
Liwei Sun ◽  
...  

The salivary gland is composed of an elegant epithelial network that secrets saliva and maintains oral homeostasis. While cell lines and animal models furthered our understanding of salivary gland biology, they cannot replicate key aspects of the human salivary gland tissue, particularly the complex architecture and microenvironmental features that dictate salivary gland function. Organoid cultures provide an alternative system to recapitulate salivary gland tissue in vitro, and salivary gland organoids have been generated from pluripotent stem cells and adult stem/progenitor cells. In this review, we describe salivary gland organoids, the advances and limitations, and the promising potential for regenerative medicine.


2005 ◽  
Vol 115 (2) ◽  
pp. 244-248 ◽  
Author(s):  
Akira Joraku ◽  
Christopher A. Sullivan ◽  
James J. Yoo ◽  
Anthony Atala

2020 ◽  
Vol 115 ◽  
pp. 275-287
Author(s):  
Sang-woo Lee ◽  
Junchul Kim ◽  
Minjae Do ◽  
Eun Namkoong ◽  
Haeshin Lee ◽  
...  

2015 ◽  
Vol 21 (11-12) ◽  
pp. 1733-1751 ◽  
Author(s):  
Andrew D. Shubin ◽  
Timothy J. Felong ◽  
Dean Graunke ◽  
Catherine E. Ovitt ◽  
Danielle S.W. Benoit

Author(s):  
Padma Pradeepa Srinivasan ◽  
Swati Pradhan-Bhatt ◽  
Mary C. Farach-Carson ◽  
Daniel A. Harrington

2020 ◽  
Vol 12 (4) ◽  
pp. 4285-4294 ◽  
Author(s):  
Sang-woo Lee ◽  
Ji Hyun Ryu ◽  
Min Jae Do ◽  
Eun Namkoong ◽  
Haeshin Lee ◽  
...  

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