Hypothetical calculations of ascorbic acid synthesis based on estimates in vitro

1980 ◽  
Vol 33 (5) ◽  
pp. 961-964 ◽  
Author(s):  
R B Rucker ◽  
M A Dubick ◽  
J Mouritsen
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Ascorbic Acid Synthesis

scholarly journals A STUDY OF ASCORBIC ACID SYNTHESIS BY ANIMAL TISSUE IN VITRO

1942 ◽  
Vol 142 (2) ◽  
pp. 529-541 ◽  
Author(s):  
C.V. Smythe ◽  
C.G. King
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Animal Tissue ◽  
Ascorbic Acid Synthesis

scholarly journals L-Ascorbic Acid Shapes Bovine Pasteurella multocida Serogroup A Infection

2021 ◽  
Vol 8 ◽  
Author(s):  
Guangfu Zhao ◽  
Pan Li ◽  
Hao Mu ◽  
Nengzhang Li ◽  
Yuanyi Peng
Keyword(s):  
Ascorbic Acid ◽  
Pasteurella Multocida ◽  
Bacterial Load ◽  
Acid Synthesis ◽  
Bacterial Density ◽  
Protective Agent ◽  
Factor Expression ◽  
Ascorbic Acid Synthesis

Bovine Pasteurella multocida serogroup A (bovine PmA) is one of the most important pathogens causing fatal pneumonia in cattle. However, it is largely unknown how nutrition shapes bovine PmA infection. Here, we discovered that the infected lung held the highest bacterial density than other tissues during infection. By screening the different metabolites between high (lung)- and low (liver)-bacterial density tissues, the present work revealed that L-ascorbic acid and L-aspartic acid directly influenced bovine P. multocida growth. Interestingly, L-ascorbic acid, which is expressed at higher levels in the infected livers, inhibited bovine PmA growth as well as virulence factor expression and promoted macrophage bactericidal activity in vitro. In addition, ascorbic acid synthesis was repressed upon bovine PmA infection, and supplementation with exogenous L-ascorbic acid significantly reduced the bacterial burden of the infected lungs and mouse mortality. Collectively, our study has profiled the metabolite difference of the murine lung and liver during bovine PmA infection. The screened L-ascorbic acid showed repression of bovine PmA growth and virulence expression in vitro and supplementation could significantly increase the survival rate of mice and reduce the bacterial load in vivo, which implied that L-ascorbic acid could serve as a potential protective agent for bovine PmA infection in clinic.

scholarly journals The Myo ‐inositol pathway does not contribute to ascorbic acid synthesis

Plant Biology ◽  
2018 ◽  
Vol 21 (S1) ◽  
pp. 95-102 ◽  
Author(s):  
E. Ivanov Kavkova ◽  
C. Blöchl ◽  
R. Tenhaken
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Ascorbic Acid Synthesis

Ascorbic Acid Synthesis with the Reconstructed Enzyme System

1961 ◽  
Vol 50 (4) ◽  
pp. 374-375 ◽  
Author(s):  
KAZUO YAMADA ◽  
KANTARO SUZUKI ◽  
YOSHITAKE MANO ◽  
NORIO SHIMAZONO
Keyword(s):  
Ascorbic Acid ◽  
Enzyme System ◽  
Acid Synthesis ◽  
Ascorbic Acid Synthesis

scholarly journals Ascorbic Acid Synthesis in Fetal and Neonatal Pigs and in Pregnant and Postpartum Sows

2001 ◽  
Vol 131 (7) ◽  
pp. 1997-2001 ◽  
Author(s):  
San Ching ◽  
Donald C. Mahan ◽  
Joseph S. Ottobre ◽  
Konrad Dabrowski
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Neonatal Pigs ◽  
Ascorbic Acid Synthesis

Ascorbic acid synthesis is stimulated by enhaced glyeogenoiysls in murine liver

1995 ◽  
Vol 78 ◽  
pp. 22
Author(s):  
L. Braun ◽  
M. Csala ◽  
G. Bánhegyi ◽  
T. Garzó ◽  
J. Mandl
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Murine Liver ◽  
Ascorbic Acid Synthesis

scholarly journals Erratum to: Rice GDP-mannose pyrophosphorylase OsVTC1-1 and OsVTC1-3 play different roles in ascorbic acid synthesis

2016 ◽  
Vol 90 (4-5) ◽  
pp. 533-533
Author(s):  
Hua Qin ◽  
Zaian Deng ◽  
Chuanyu Zhang ◽  
Yayun Wang ◽  
Juan Wang ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Ascorbic Acid Synthesis

Impairment of Ascorbic Acid Synthesis in Liver Extracts of Magnesium-Deficient Rats

1983 ◽  
Vol 113 (10) ◽  
pp. 2041-2047 ◽  
Author(s):  
Jeng M. Hsu ◽  
J. Cecil Smith ◽  
A. A. Yunice ◽  
G. Kepford
Keyword(s):  
Ascorbic Acid ◽  
Acid Synthesis ◽  
Ascorbic Acid Synthesis

The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of l-ascorbic acid: Synthesis, cytostatic, and antiviral activity evaluations

2007 ◽  
Vol 15 (2) ◽  
pp. 749-758 ◽  
Author(s):  
Tatjana Gazivoda ◽  
Silvana Raić-Malić ◽  
Marko Marjanović ◽  
Marijeta Kralj ◽  
Krešimir Pavelić ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Antiviral Activity ◽  
Acid Synthesis ◽  
The Novel ◽  
Uracil Derivatives ◽  
Ascorbic Acid Synthesis ◽  
Derivatives Of
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