Vitamin E supplementation effect on human platelet function, arachidonic acid metabolism, and plasma prostacyclin levels

1988 ◽  
Vol 47 (4) ◽  
pp. 700-706 ◽  
Author(s):  
M J Stampfer ◽  
J A Jakubowski ◽  
D Faigel ◽  
R Vaillancourt ◽  
D Deykin
Keyword(s):  
Arachidonic Acid ◽  
Vitamin E ◽  
Platelet Function ◽  
Acid Metabolism ◽  
Human Platelet ◽  
Arachidonic Acid Metabolism ◽  
Vitamin E Supplementation

Influence of Antioxidants on Arachidonic Acid Metabolism and Platelet Function

1994 ◽  
Vol 51 (1) ◽  
pp. 74-79 ◽  
Author(s):  
G.H.R. Rao ◽  
M.R. Tate ◽  
M. Murthy ◽  
R.P. Hebbel ◽  
J.G. White
Keyword(s):  
Arachidonic Acid ◽  
Platelet Function ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism

Modification of platelet function and arachidonic acid metabolism by bioflavonoids

1984 ◽  
Vol 33 (9) ◽  
pp. 1525-1530 ◽  
Author(s):  
Raffaele Landolfi ◽  
Richard L. Mower ◽  
Manfred Steiner
Keyword(s):  
Arachidonic Acid ◽  
Platelet Function ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism

scholarly journals The influence of albumin and calcium on human platelet arachidonic acid metabolism

Blood ◽  
1980 ◽  
Vol 55 (3) ◽  
pp. 418-423 ◽  
Author(s):  
MJ Stuart ◽  
JM Gerrard ◽  
JG White
Keyword(s):  
Arachidonic Acid ◽  
Acid Metabolism ◽  
Human Platelet ◽  
Arachidonic Acid Metabolism ◽  
Albumin Concentration ◽  
Arachidonic Acid Release ◽  
Acid Release ◽  
External Calcium ◽  
Platelet Thromboxane

Abstract The effects of in vitro changes in calcium and albumin on human platelet arachidonic acid metabolism were evaluated. Hypoalbuminemia enhanced the conversion of released 14C-arachidonic acid from prelabeled platelet phospholipids to the metabolites of the platelet cyclooxygenase and lipoxygenase pathways. This effect was, however, associated with a decreased release of arachidonic acid in the presence of hypoalbuminemia, such that the overall conversion of released 14C- arachidonic acid to platelet thromboxane B2 was similar in the presence of physiologic albumin concentration (3.5 g/dl) or at decreased albumin concentrations of 0.7 and 0.0 g/dl. External calcium was shown to be important for optimal platelet arachidonic acid release, with maximal release occurring at 1 mM calcium.

Altered platelet function in cirrhosis of the liver: Impairment of inositol lipid and arachidonic acid metabolism in response to agonists

Hepatology ◽  
1988 ◽  
Vol 8 (6) ◽  
pp. 1620-1626 ◽  
Author(s):  
Giacomo Laffi ◽  
Fabio Cominelli ◽  
Marco Ruggiero ◽  
Sandra Fedi ◽  
Vincenzo P. Chiarugi ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Platelet Function ◽  
Acid Metabolism ◽  
Arachidonic Acid Metabolism ◽  
Cirrhosis Of The Liver ◽  
Liver Impairment
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