Clear Cell Carcinoma Arising in Pleomorphic Adenoma of the Salivary Gland

AbstractMalignant change arising in pleomorphic adenoma of the salivary glands is uncommon, with a reported incidence of 2–10 per cent.Only one case where a pleomorphic adenoma became a clear cell carcinoma appears to have been published in the English literature. An additional case of clear cell carcinoma arising in pleomorphic adenoma of a minor salivary gland is reported and the relevant literature discussed.

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Clear cell carcinoma arising in a pleomorphic adenoma of the submandibular gland

The Journal of Laryngology & Otology ◽

10.1017/s0022215100127331 ◽

1994 ◽

Vol 108 (6) ◽

pp. 529-532 ◽

Cited By ~ 13

Author(s):

Michael Cassidy ◽

Charles E. Connolly

Keyword(s):

Salivary Gland ◽

Cell Carcinoma ◽

Submandibular Gland ◽

Pleomorphic Adenoma ◽

Clear Cell ◽

Clear Cell Carcinoma ◽

Tumour Progression ◽

Rare Neoplasm ◽

Immunohistochemical Profile ◽

Rapid Tumour

AbstractClear cell carcinoma of salivary gland is a rare neoplasm. We report a third case of clear cell carcinoma arising in a pleomorphic adenoma and also in an extraparotid location. We document the immunohistochemical profile of the tumour including reactivity with a marker for the c-erbh-2 oncoprotein and suggest a myoepithelial origin for these lesions. The presence of a tetraploid stemline may account for the rapid tumour progression in this case.

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Salivary gland clear cell carcinoma with delayed lung metastases after 13 years: a case report

10.26226/morressier.5b4709856f4cb30010951d1e ◽

2018 ◽

Author(s):

Sónia Dias Carvalho

Keyword(s):

Salivary Gland ◽

Case Report ◽

Cell Carcinoma ◽

Clear Cell ◽

Clear Cell Carcinoma ◽

Lung Metastases

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Hyalinizing clear cell carcinoma of the nasopharynx operated by trans-oral and trans-palatal approach

The Journal of Laryngology & Otology ◽

10.1017/s0022215114002485 ◽

2015 ◽

Vol 129 (S2) ◽

pp. S95-S97 ◽

Cited By ~ 2

Author(s):

T Nakashima ◽

R Yasumatsu ◽

M Yamauchi ◽

S Toh ◽

T Nakano ◽

...

Keyword(s):

Salivary Gland ◽

Cell Carcinoma ◽

Surgical Resection ◽

Clear Cell ◽

Clear Cell Carcinoma ◽

Minor Salivary Gland ◽

Good Prognosis ◽

Salivary Gland Neoplasm ◽

Hyalinizing Clear Cell Carcinoma

AbstractBackground:Hyalinizing clear cell carcinoma is a rare minor salivary gland neoplasm. The treatment of choice is surgical resection with or without post-operative radiotherapy. This tumour often demonstrates a good prognosis.Case report:We report a case of hyalinizing clear cell carcinoma arising in the nasopharynx. A 27-year-old female presented with progressive hearing disturbance and tinnitus. On examination, an expansile mass was observed in her nasopharynx. Biopsy was performed and the pathology results returned as clear cell carcinoma.Results and conclusion:Surgical resection was performed trans-orally accompanied by trans-palatal approach. She has no recurrence during more than two years of follow up.

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