Altered drug infusion rates during syringe-pump infusion

Objective Preparation of drug solutions used with electronic syringe infusion pumps plays a crucial role in the delivery of an accurate drug concentration. Is there a correlation between drug concentrations during syringe pump infusion and preparation protocols? Method Norepinephrine, insulin, and sufentanil were prepared in 3 different ways: (1) the drug was taken from the vial, then the solvent was added followed by an air bubble, and mixing was performed by turning the syringe top-to-bottom in a 180° shaking movement 5 consecutive times; (2) the drug was taken from the vial, then the solvent was added and not mixed; and (3) the solvent was taken from a stock solution, then the drug was added and not mixed. Concentrations of drugs were determined at different times during administration by reverse-phase high-performance liquid chromatography with ultraviolet detection. All analyses were performed in triplicate and were based on measurement of peak areas. Results With no shaking of the syringe, the concentration of the injected drugs varies widely. In any case, mixing of the syringe contents by turning the syringe in a top-to-bottom 180° shaking movement 5 times with an air bubble would ensure administration of the drug at a constant concentration. Conclusions Without mixing, the concentrations of all drug solutions varied widely when administered via an electronic syringe infusion pump. Mixing syringe contents should be made part of the compulsory curriculum for administering medications at all levels of medical education. (Critical Care Nurse. 2016;36[4]:36–45)

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Influence of syringe pump infusion line compliance on drug delivery during acute line loop formation

European Journal of Anaesthesiology ◽

10.1097/00003643-200000002-00453 ◽

2000 ◽

Vol 17 (Supplement 19) ◽

pp. 139

Author(s):

M. Weiss ◽

S. Fanconi ◽

T. Neff ◽

O. Banziger

Keyword(s):

Drug Delivery ◽

Syringe Pump ◽

Loop Formation ◽

Infusion Line ◽

Syringe Pump Infusion ◽

Pump Infusion

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Cost and acceptability of three syringe-pump infusion systems

American Journal of Health-System Pharmacy ◽

10.1093/ajhp/47.8.1794 ◽

1990 ◽

Vol 47 (8) ◽

pp. 1794-1798

Author(s):

Mark S. Johnson ◽

Lawrence J. Pesko ◽

Clifton F. Wood ◽

Thomas P. Reinders

Keyword(s):

Syringe Pump ◽

Infusion Systems ◽

Syringe Pump Infusion ◽

Pump Infusion

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Pharmacy-initiated implementation of a syringe pump infusion system

American Journal of Health-System Pharmacy ◽

10.1093/ajhp/42.3.584 ◽

1985 ◽

Vol 42 (3) ◽

pp. 584-587

Author(s):

Jeanette Bousquet Goudreau ◽

Joseph M. Morrissey

Keyword(s):

Syringe Pump ◽

Syringe Pump Infusion ◽

Infusion System ◽

Pump Infusion

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A REVIEW ON PATIENT-CONTROLLED ANALGESIA INFUSION SYSTEM

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2017.v10s1.19588 ◽

2017 ◽

Vol 10 (13) ◽

pp. 117

Author(s):

Usha Rani Shola ◽

Neela Narayanan V

Keyword(s):

Intelligent Systems ◽

Continuous Monitoring ◽

Patient Monitoring ◽

Quality Care ◽

Infusion Pump ◽

Care Process ◽

Patient Controlled Analgesia ◽

Drug Infusion ◽

Infusion System ◽

Pump Infusion

PCA is a patient-controlled analgesia infusion pump, which is used to infuse the medicine into the patients after surgery. It contains a syringe with pain medicine to infuse that is prescribed by the physician. The drugs used for pain control are high-alert medicines, since overmedication may cause death to the patients. These types of unbearable events may happen due to medical errors, prescription errors, adverse events (AEs), etc. Hence, it requires a precautionary attention or continuous monitoring for PCA pump infusion patients. However, always physicians or nurses may not monitor a patient continuously. To provide safety to the patient, the PCA pump needs a smart care process to alert the physician. This study represents the survey on PCA pump errors, AEs, and solutions for it to avoid them. The solution will automatically alert the infusion-related situation of the patients, those are taking the intravenous drug infusion at different procedure rooms in the hospitals. Moreover, it increases the safety to infusion pump with advances of decision-making in health, patient monitoring, alert notification to nursing, and productivity. This quality care can be achieved by integrating the PCA pump with other intelligent systems.

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