Low-cost syringe pump design modification for Minimum Quantity of Lubrication system application

2017 ◽  
Author(s):  
Anderson Nakazato ◽  
Maurício Oliveira FIlho ◽  
Marcel Kondo ◽  
Manoel Alves ◽  
Luis Hein
Keyword(s):  
System Application ◽  
Low Cost ◽  
Lubrication System ◽  
Syringe Pump ◽  
Design Modification ◽  
Pump Design ◽  
Minimum Quantity ◽  
Minimum Quantity Of Lubrication

scholarly journals SpheroidPicker for automated 3D cell culture manipulation using deep learning

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Istvan Grexa ◽  
Akos Diosdi ◽  
Maria Harmati ◽  
Andras Kriston ◽  
Nikita Moshkov ◽  
...  
Keyword(s):  
Cell Culture ◽  
Precision Medicine ◽  
High Throughput Screening ◽  
Standard Sample ◽  
Ex Vivo ◽  
Low Cost ◽  
3D Cell Culture ◽  
Syringe Pump ◽  
Experimental Conditions ◽  
The Past

AbstractRecent statistics report that more than 3.7 million new cases of cancer occur in Europe yearly, and the disease accounts for approximately 20% of all deaths. High-throughput screening of cancer cell cultures has dominated the search for novel, effective anticancer therapies in the past decades. Recently, functional assays with patient-derived ex vivo 3D cell culture have gained importance for drug discovery and precision medicine. We recently evaluated the major advancements and needs for the 3D cell culture screening, and concluded that strictly standardized and robust sample preparation is the most desired development. Here we propose an artificial intelligence-guided low-cost 3D cell culture delivery system. It consists of a light microscope, a micromanipulator, a syringe pump, and a controller computer. The system performs morphology-based feature analysis on spheroids and can select uniform sized or shaped spheroids to transfer them between various sample holders. It can select the samples from standard sample holders, including Petri dishes and microwell plates, and then transfer them to a variety of holders up to 384 well plates. The device performs reliable semi- and fully automated spheroid transfer. This results in highly controlled experimental conditions and eliminates non-trivial side effects of sample variability that is a key aspect towards next-generation precision medicine.

scholarly journals Low-cost touchscreen driven programmable dual syringe pump for life science applications

HardwareX ◽  
2018 ◽  
Vol 4 ◽  
pp. e00027 ◽  
Author(s):  
Valentina E. Garcia ◽  
Jamin Liu ◽  
Joseph L. DeRisi
Keyword(s):  
Life Science ◽  
Low Cost ◽  
Syringe Pump

The Effect of Air Injection Method on the Airlift Pump Performance

2012 ◽  
Vol 134 (11) ◽  
Author(s):  
Dong Hu ◽  
Chuan-Lin Tang ◽  
Shu-Peng Cai ◽  
Feng-Hua Zhang
Keyword(s):  
Flow Rate ◽  
Volume Flow Rate ◽  
Low Cost ◽  
Air Injection ◽  
Water Volume ◽  
Pump Design ◽  
Pump Performance ◽  
Dimensionless Equation ◽  
Measurement Results ◽  
Injection Methods

With simple structure, excellent reliability, low cost, no restriction at depth of water, and easy control and operation, airlift pumps have special advantage in borehole hydraulic jet mining, river dredging and deep sea mining. To clarify the mechanism and process of action of air injection methods on air lift performance, and to enhance lifting capacity, the pump performance of a small airlift system in transporting river sands is investigated experimentally in the present study. The results are as the follows. The influences of air exit ports on water volume flow rate, mass flow rate of solids and lifting efficiency are studied and found to be very low when the number of air exit ports exceeds 3. The pump design show best pumping capability for water and solids at higher air flow rates, but the lifting efficiency is then very low. In addition, a dimensionless equation which describes the flows in the pipe is presented based on the Bernoulli equation, and compared with measurement results in the dimensionless form, which are nearly in good agreement with each other for all the arrangements of air exit ports and are basically contained within ±18% of the theoretical curve. The results are important for understanding the mechanism of airlift pumps and enriching multiphase flow theory.

scholarly journals Low-Cost, Modular Modification to a Desktop 3D Printer for General Purpose Gel/Paste Extrusion & Direct Ink Writing

2021 ◽  
Author(s):  
D. J. Leech ◽  
S. Lightfoot ◽  
D. Huson ◽  
A. Stratakos
Keyword(s):  
Low Cost ◽  
Biological Materials ◽  
General Purpose ◽  
3D Printer ◽  
Syringe Pump ◽  
Selective Deposition ◽  
Direct Ink Writing ◽  
Driven System ◽  
Paste Extrusion

AbstractWe propose a design for a simple paste extruder modification that can be used for the selective deposition and patterning of gels and pastes, using a desktop 3D printer as the primary platform. This technology has found use with a variety of materials in seemingly disparate fields, including the printing of ceramics, food and biological materials, each with a variety of material-specific solutions to enhance printability. However, we focus on a syringe-pump driven system that is simple, low-cost, modular, easily assembled and highly modifiable with a low barrier of entry in order to maximise the generalisability and range of printable materials.

Subcutaneous Dihydrocodeine Tartrate: Compatibility in a Syringe Pump With Other Drugs Frequently Prescribed for the Management of Symptoms Associated With Brain Tumors

2021 ◽  
pp. 082585972110527
Author(s):  
Ruth Isherwood ◽  
Amy Forsyth ◽  
Anne Wilson
Keyword(s):  
Sodium Chloride ◽  
Brain Tumors ◽  
Physical Stability ◽  
Syringe Pump ◽  
Pump Design ◽  
Subcutaneous Infusion ◽  
Hyoscine Butylbromide ◽  
Stability Data ◽  
Future Work ◽  
Different Doses

Background Dihydrocodeine can be more effective in the management of headache due to brain tumor than other opioids. It can be used as a subcutaneous infusion, but at present, there is little available data to support its use in combination with other medicines in a syringe pump. Aim This project aimed to establish physical stability data for the use of dihydrocodeine with other drugs when combined in a syringe pump. Design: Dihydrocodeine was combined in a syringe pump with either cyclizine, midazolam, or hyoscine butylbromide at different doses chosen to represent routine clinical practice. Each drug combination was repeated twice—with 0.9% sodium chloride and with water for injections. Setting: The project was conducted in an independent hospice after seeking appropriate approvals to use the drugs for this purpose. Results Dihydrocodeine and midazolam appear compatible at when 0.9% sodium chloride is used as the diluent. Dihydrocodeine and cyclizine appeared compatible when either 0.9% saline or water for injections was used as the diluent. Dihydrocodeine and hyoscine butylbromide appeared compatible with either diluent at 24 hours. Conclusions Physical stability data has been described that will support the use of dihydrocodeine and other drugs that are commonly used to manage symptoms due to brain tumors at the end of life. This information will benefit patients and ensure that one syringe pump can be used where possible. Future work could expand on this data and explore the physical stability of three drug combinations in each syringe.

Performance of Low Cost 3D Printed Minimum Quantity Lubrication Applicator Using Palm Oil in Milling Steel

2020 ◽  
Vol 997 ◽  
pp. 85-92
Author(s):  
Abang Mohammad Nizam Abang Kamaruddin ◽  
Abdullah Yassin ◽  
Shahrol Mohamaddan ◽  
Syaiful Anwar Rajaie ◽  
Muhammad Isyraf Mazlan ◽  
...  
Keyword(s):  
Tool Wear ◽  
Cutting Forces ◽  
Cutting Tool ◽  
Low Cost ◽  
Minimum Quantity Lubrication ◽  
Machining Process ◽  
Cutting Condition ◽  
Dry Cutting ◽  
Minimum Quantity ◽  
Tool Performance

One of the most significant factors in machining process or metal cutting is the cutting tool performance. The rapid wear rate of cutting tools and cutting forces expend due to high cutting temperature is a critical problem to be solved in high-speed machining process, milling. Near-dry machining such as minimum quantity lubrication (MQL) is regarded as one of the solutions to solve this problem. However, the function of MQL in milling process is still uncertain so far which prevents MQL from widely being utilized in this specific machining process. In this paper, the mechanism of cutting tool performance such as tool wear and cutting forces in MQL assisted milling is investigated more comprehensively and the results are compared in three different cutting conditions which is dry cutting, wet cutting (flooding) and MQL. The MQL applicator is constructed from a household grade low-cost 3D printing technique. The chips surface of chips formation in each cutting condition is also observed using Scanning Electron Microscopy (SEM) machine. It is found out that wet cutting (flooding) is the best cutting performance compare to MQL and dry cutting. However, it can also be said that wet cutting and MQL produced almost the same value of tool wear and cutting forces as there is negligible differences in average tool wear and cutting forces between them based on the experiment conducted.

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