A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients

Desmoid tumors (deep fibromatosis) of the mesentery are rare mesenchymal tumors. They are often misdiagnosed, especially with a previous history of resection for gastrointestinal stromal tumor (GIST). Immunohistochemistry can help differentiate between these two tumors. In this article, we present a case we had encountered: a Desmoid tumor developing in a patient with a history of GIST 3 years ago. It is the first case of GIST with subsequent development of Desmoid tumor to be reported in Saudi Arabia. We discuss the two entities of Desmoid tumor and GIST by comparing their definitions, clinical presentations, histological features, immunohistochemistry stains, molecular pathogenesis, prognosis, and treatment. We also discuss the relationship between GIST and the subsequent development of Desmoid tumors and compare our case with case reports in literature.

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Endoscopic full-thickness resection of gastric gastrointestinal stromal tumor: a Japanese case series

Annals of Gastroenterology ◽

10.20524/aog.2019.0413 ◽

2019 ◽

Cited By ~ 1

Author(s):

Satoki Shichijo

Keyword(s):

Gastrointestinal Stromal Tumor ◽

Case Series ◽

Stromal Tumor ◽

Full Thickness ◽

Japanese Case ◽

Endoscopic Full Thickness Resection

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Ovarian Cancer Metastases Mimicking Gastrointestinal Stromal Tumor: A Case Series

The American Journal of Gastroenterology ◽

10.14309/00000434-201610001-02292 ◽

2016 ◽

Vol 111 ◽

pp. S1109-S1110

Author(s):

Umar Hayat ◽

Ari Garber ◽

Bradley Confer ◽

Tyler Stevens ◽

John Vargo ◽

...

Keyword(s):

Ovarian Cancer ◽

Gastrointestinal Stromal Tumor ◽

Case Series ◽

Stromal Tumor ◽

Cancer Metastases

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An Intra-Abdominal Desmoid Tumor, Embedded in the Pancreas, Preoperatively Diagnosed as an Extragastric Growing Gastrointestinal Stromal Tumor

Case Reports in Oncology ◽

10.1159/000468983 ◽

2017 ◽

Vol 10 (1) ◽

pp. 301-307 ◽

Cited By ~ 7

Author(s):

Mari Mizuno ◽

Yoshiaki Kawaguchi ◽

Aya Kawanishi ◽

Yohei Kawashima ◽

Atsuko Maruno ◽

...

Keyword(s):

Gastrointestinal Stromal Tumor ◽

Desmoid Tumor ◽

Abdominal Cavity ◽

Partial Gastrectomy ◽

Abdominal Ultrasound ◽

Needle Aspiration ◽

Stromal Tumor ◽

Conversion To Open Surgery ◽

Enhanced Computed Tomography ◽

Abdominal Desmoid Tumor

A 45-year-old woman was found to have a pancreatic tumor by abdominal ultrasound performed for a medical check-up. Abdominal contrast-enhanced computed tomography showed a hypovascular tumor measuring 30 mm in diameter in the pancreatic tail. Endoscopic ultrasound-guided fine needle aspiration was performed. An extragastric growing gastrointestinal stromal tumor was thereby diagnosed preoperatively, and surgical resection was planned. Laparoscopic surgery was attempted but conversion to open surgery was necessitated by extensive adhesions, and distal pancreatectomy, splenectomy, and partial gastrectomy were performed. The histological diagnosis was an intra-abdominal desmoid tumor. A desmoid tumor is a fibrous soft tissue tumor arising in the fascia and musculoaponeurotic tissues. It usually occurs in the extremities and abdominal wall, and only rarely in the abdominal cavity. We experienced a case with an intra-abdominal desmoid tumor that was histologically diagnosed after laparotomy, which had been preoperatively diagnosed as an extragastric growing gastrointestinal stromal tumor. Although rare, desmoid tumors should be considered in the differential diagnosis of intra-abdominal tumors. Herein, we report this case with a literature review.

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