A phase II study of dose-escalation of regorafenib for patients with previously treated metastatic colorectal cancer – DEREGULATE study - Trial in progress

Annals of Oncology ◽

10.1093/annonc/mdy151.291 ◽

2018 ◽

Vol 29 ◽

pp. v82

Author(s):

K. Kawaguchi ◽

R. Nishitai ◽

D. Manaka ◽

T. Ota ◽

Y. Nishikawa ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Dose Escalation ◽

Phase Ii Study ◽

Study Trial ◽

Previously Treated

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Phase II study of capecitabine, oxaliplatin and erlotinib in previously treated patients with metastatic colorectal cancer (MCRC)

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.14_suppl.3580 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3580-3580 ◽

Author(s):

J. A. Meyerhardt ◽

A. Xhu ◽

P. C. Enzinger ◽

D. P. Ryan ◽

J. W. Clark ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Previously Treated Patients ◽

Previously Treated

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Randomized phase II study of regorafenib followed by cetuximab versus reverse sequence for wild-type KRAS metastatic colorectal cancer previously treated with fluoropyrimidine, oxaliplatin, and irinotecan (REVERCE).

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.tps3662 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. TPS3662-TPS3662

Author(s):

Kohei Shitara ◽

Kentaro Yamazaki ◽

Hiroyuki Uetake ◽

Takeshi Kato ◽

Eiji Oki ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Wild Type ◽

Randomized Phase Ii ◽

Reverse Sequence ◽

Previously Treated

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REVERCE: Randomized phase II study of regorafenib followed by cetuximab versus the reverse sequence for metastatic colorectal cancer patients previously treated with fluoropyrimidine, oxaliplatin, and irinotecan—Biomarker analysis.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.3510 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. 3510-3510 ◽

Author(s):

Yasushi Tsuji ◽

Kohei Shitara ◽

Takeharu Yamanaka ◽

Tadamichi Denda ◽

Katsunori Shinozaki ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Cancer Patients ◽

Phase Ii ◽

Phase Ii Study ◽

Randomized Phase Ii ◽

Biomarker Analysis ◽

Reverse Sequence ◽

Previously Treated ◽

Colorectal Cancer Patients

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P-272 Phase II study of Regorafenib as single agent for the treatment of patients with metastatic colorectal cancer with any RAS or BRAF mutation and previously treated with FOLFOXIRI plus bevacizumab

Annals of Oncology ◽

10.1093/annonc/mdv233.269 ◽

2015 ◽

Vol 26 ◽

pp. iv80

Author(s):

P. García Alfonso ◽

M.J. Ortiz ◽

G. Durán ◽

E. Falcó ◽

A. Muñoz ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Braf Mutation ◽

Phase Ii Study ◽

Single Agent ◽

Previously Treated

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Phase II study of bevacizumab and irinotecan as second-line therapy for patients with metastatic colorectal cancer previously treated with fluoropyrimidines, oxaliplatin, and bevacizumab

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-017-3255-3 ◽

2017 ◽

Vol 79 (3) ◽

pp. 579-585 ◽

Author(s):

Hidekazu Kuramochi ◽

Masayuki Ando ◽

Michio Itabashi ◽

Go Nakajima ◽

Kazuyuki Kawakami ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Second Line ◽

Second Line Therapy ◽

Line Therapy ◽

Previously Treated

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Abstract CT124: A phase II study of bevacizumab and irinotecan as second-line therapy for patients with metastatic colorectal cancer previously treated with fluoropyrimidine, oxaliplatin, and bevacizumab

10.1158/1538-7445.am2016-ct124 ◽

2016 ◽

Author(s):

Go Nakajima ◽

Hidekazu Kuramochi ◽

Masayuki Ando ◽

Michio Itabashi ◽

Kazuyuki Kawakami ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Second Line ◽

Second Line Therapy ◽

Line Therapy ◽

Previously Treated

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Phase II study of capecitabine, oxaliplatin and erlotinib in previously treated patients with metastatic colorectal cancer (MCRC)

Journal of Clinical Oncology ◽

10.1200/jco.2004.22.90140.3580 ◽

2004 ◽

Vol 22 (14_suppl) ◽

pp. 3580-3580 ◽

Author(s):

J. A. Meyerhardt ◽

A. Xhu ◽

P. C. Enzinger ◽

D. P. Ryan ◽

J. W. Clark ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Previously Treated Patients ◽

Previously Treated

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3070 POSTER Bevacizumab in patients with previously treated metastatic colorectal cancer: preliminary results of a phase II study (bevacolor)

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(07)70998-9 ◽

2007 ◽

Vol 5 (4) ◽

pp. 257

Author(s):

C. Borg ◽

J.P. Delord ◽

F. Husseini ◽

V. Trillet Lenoir ◽

R. Faroux ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Preliminary Results ◽

Previously Treated

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A Phase II Study of Modified deGramont 5-Fluorouracil, Leucovorin, and Oxaliplatin in Previously Treated Patients with Metastatic Colorectal Cancer

Cancer Investigation ◽

10.1081/cnv-120022359 ◽

2003 ◽

Vol 21 (4) ◽

pp. 505-511 ◽

Author(s):

David P. Ryan ◽

Jeffrey W. Clark ◽

Matthew H. Kulke ◽

Charles S. Fuchs ◽

Craig C. Earle ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Phase Ii ◽

Phase Ii Study ◽

Previously Treated Patients ◽

Previously Treated

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REVERCE: a randomized phase II study of regorafenib followed by cetuximab versus the reverse sequence for previously treated metastatic colorectal cancer patients

Annals of Oncology ◽

10.1093/annonc/mdy526 ◽

2019 ◽

Vol 30 (2) ◽

pp. 259-265 ◽

Author(s):

K. Shitara ◽

T. Yamanaka ◽

T. Denda ◽

Y. Tsuji ◽

K. Shinozaki ◽

...

Keyword(s):

Colorectal Cancer ◽

Metastatic Colorectal Cancer ◽

Cancer Patients ◽

Phase Ii ◽

Phase Ii Study ◽

Randomized Phase Ii ◽

Reverse Sequence ◽

Previously Treated ◽

Colorectal Cancer Patients

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