Colorectal Cancer Patients
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2021 ◽  
Vol 41 (12) ◽  
pp. 5903-5912

2021 ◽  
Vol 28 (4) ◽  
pp. 530-538
Hae Jeong An ◽  
Sook Jung Kang

Purpose: The purpose of this study was to identify the influence of self-esteem and sexual communication on sexual satisfaction among female colorectal cancer patients with ostomy.Methods: A cross-sectional descriptive study was conducted using self-reported online questionnaires. The participants were 85 women with colorectal cancer who had undergone ostomy formation surgery. Data were analyzed using descriptive statistics, the t-test, analysis of variance, the Scheffé test, correlation coefficients, and hierarchical multiple regression with SPSS version 26.0.Results: The mean sexual satisfaction score was 2.79±0.73 (range, 0~5). There was no significant relationship between self-esteem and sexual satisfaction. Sexual communication had a significant correlation with sexual satisfaction (r=.83, p<.001) and was a strong predictor of sexual satisfaction (β=.83, p<.001).Conclusion: The findings of this study indicate that colorectal cancer patients with ostomy experience low sexual satisfaction and that sexual communication is a meaningful factor for sexual satisfaction. Accordingly, nurses need to factor in sexual issues when caring for patients, and should encourage both patients and their partners to participate in education related to sexual health. It will also be helpful to inform patients about the importance of sexual communication with their partners as a sustainable intervention.

2021 ◽  
Vol 19 (1) ◽  
You Zou ◽  
Shuang Liu ◽  
Jianhong Wu ◽  
Zhen Sun

Abstract Background Capecitabine is a prodrug that is enzymatically converted to its active form, fluorouracil (also called 5-fluorouracil), which is commonly used as adjuvant chemotherapy in colorectal cancer patients. Severe gastrointestinal bleeding induced by capecitabine is rare. Here, we are presenting the first case report of surgery specimen assisted diagnosis of this uncommon condition. Case presentation A 63-year-old Chinese male with a history of colon adenocarcinoma and right hemicolectomy presented with severe lower gastrointestinal bleeding 2 days after finishing capecitabine administration during the first cycle of XELOX adjuvant chemotherapy. Because of the negative findings of active bleeding points by digital subtraction angiography (DSA) or colonoscopy, emergency laparotomy and partial enterectomy were performed. The bloody diarrhea had resolved after surgery and a terminal ileitis was diagnosed after pathological examination of the surgical specimen. Conclusions Terminal ileitis induced by capecitabine is likely to be underreported. It should be considered more often as a cause of severe gastrointestinal bleeding during or after treatment with capecitabine agents. Emergency surgery may achieve satisfactory outcomes if endoscopic hemostasis is ineffective. Highlights of this case 1. Gastrointestinal bleeding following capecitabine treatment in colorectal cancer patients might be life-threatening. 2. Terminal ileitis induced by capecitabine should always be considered in the differential diagnosis of severe gastrointestinal bleeding. 3. Awareness of the risk factors such as deficiency of dihydropyrimidine dehydrogenase, advanced age, or right colectomy may aid in reducing capecitabine-related morbidity. 4. When severe bleeding occurs, emergency surgery may achieve satisfactory outcomes if medical and endoscopic interventions are ineffective.

Barbara Romano ◽  
Ester Pagano ◽  
Fabio A. Iannotti ◽  
Fabiana Piscitelli ◽  
Vincenzo Brancaleone ◽  

2021 ◽  
Vol 9 (32) ◽  
pp. 9804-9814
Dadang Makmun ◽  
Marcellus Simadibrata ◽  
Murdani Abdullah ◽  
Ari F Syam ◽  
Hamzah Shatri ◽  

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