scholarly journals Dual-Task Performance in Alzheimer's Disease, Mild Cognitive Impairment, and Normal Ageing

2011 ◽  
Vol 26 (4) ◽  
pp. 340-348 ◽  
Author(s):  
J. A. Foley ◽  
R. Kaschel ◽  
R. H. Logie ◽  
S. Della Sala
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Task Performance ◽  
Dual Task ◽  
Dual Task Performance ◽  
Normal Ageing

scholarly journals Dual task performance in early Alzheimer's disease, amnestic mild cognitive impairment and depression

2008 ◽  
Vol 39 (1) ◽  
pp. 23-31 ◽  
Author(s):  
J. A. Lonie ◽  
K. M. Tierney ◽  
L. L. Herrmann ◽  
C. Donaghey ◽  
R. E. O'Carroll ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Task Performance ◽  
Dual Task ◽  
Amnestic Mild Cognitive Impairment ◽  
Dual Task Performance ◽  
Dual Task Paradigm ◽  
Early Alzheimer’S Disease

BackgroundThe dual task paradigm (Baddeleyet al.1986; Della Salaet al.1995) has been proposed as a sensitive measure of Alzheimer's dementia, early in the disease process.MethodWe investigated this claim by administering the modified dual task paradigm (utilising a pencil-and-paper version of a tracking task) to 33 patients with amnestic mild cognitive impairment (aMCI) and 10 with very early Alzheimer's disease, as well as 21 healthy elderly subjects and 17 controls with depressive symptoms. All groups were closely matched for age and pre-morbid intellectual ability.ResultsThere were no group differences in dual task performance, despite poor performance in episodic memory tests of the aMCI and early Alzheimer's disease groups. In contrast, the Alzheimer patients were specifically impaired in the trail-making test B, another commonly used test of divided attention.ConclusionsThe dual task paradigm lacks sensitivity for use in the early differential diagnosis of Alzheimer's disease.

scholarly journals Dual Task Impairments in Vascular Dementia

2010 ◽  
Vol 22 (1-2) ◽  
pp. 45-52 ◽  
Author(s):  
Kate Inasaridze ◽  
Jennifer A. Foley ◽  
Robert H. Logie ◽  
Sergio Della Sala
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Episodic Memory ◽  
Vascular Dementia ◽  
Task Performance ◽  
Dual Task ◽  
Dual Tasking ◽  
Dual Task Performance ◽  
Significant Impairment ◽  
Normal Ageing

Several studies have shown that people with Alzheimer's disease (AD) demonstrate difficulties in doing two things at once or 'dual-tasking' and that this dual task impairment is insensitive to normal ageing, chronic depression or prodromal conditions like Mild Cognitive Impairment. It is not known, however, if this impairment is specific to AD, or also present in other dementias, such as vascular dementia (VaD). In this study 15 people with VaD, 25 healthy age-matched and 25 healthy young controls were assessed using a paper and pencil dual tasking paradigm and several measures of working and episodic memory. Age had no effect on dual task performance, but the VaD patients demonstrated a significant impairment in dual tasking ability. Performance on the memory measures was instead affected by age with a further deterioration in the VaD patients. Both dual tasking and memory ability were significantly correlated with disease severity, as assessed by the MMSE. These results indicate that performance on the dual task could be a specific indicator of pathological ageing.

P4-158: Dual-task gait performance in mild cognitive impairment may predict Alzheimer's disease conversion

2013 ◽  
Vol 9 ◽  
pp. P764-P764
Author(s):  
Mei Sian Chong ◽  
Laura Tay ◽  
Peng Chew Mark Chan ◽  
Noorhazlina Ali ◽  
Pamela Chew ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Dual Task ◽  
Gait Performance

scholarly journals Dual-task as a predictor of falls in older people with mild cognitive impairment and mild Alzheimer's disease: a prospective cohort study

2018 ◽  
Vol 22 (5) ◽  
pp. 417-423 ◽  
Author(s):  
Jessica Gonçalves ◽  
Juliana Hotta Ansai ◽  
Fernando Arturo Arriagada Masse ◽  
Francisco Assis Carvalho Vale ◽  
Anielle Cristhine de Medeiros Takahashi ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cohort Study ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Older People ◽  
Prospective Cohort Study ◽  
Dual Task ◽  
Prospective Cohort

scholarly journals The cerebellum shrinks faster than normal ageing in Alzheimer's disease but not in mild cognitive impairment

2017 ◽  
Vol 38 (6) ◽  
pp. 3141-3150 ◽  
Author(s):  
Hossein Tabatabaei-Jafari ◽  
Erin Walsh ◽  
Marnie E. Shaw ◽  
Nicolas Cherbuin ◽  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Normal Ageing

scholarly journals Gait, dual task and history of falls in elderly with preserved cognition, mild cognitive impairment, and mild Alzheimer's disease

2017 ◽  
Vol 21 (2) ◽  
pp. 144-151 ◽  
Author(s):  
Juliana H. Ansai ◽  
Larissa P. Andrade ◽  
Paulo G. Rossi ◽  
Anielle C.M. Takahashi ◽  
Francisco A.C. Vale ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Dual Task ◽  
History Of ◽  
Falls In Elderly

Associations between physical function, dual-task performance and cognition in patients with mild Alzheimer's disease

2015 ◽  
Vol 20 (11) ◽  
pp. 1139-1146 ◽  
Author(s):  
Nanna Aue Sobol ◽  
Kristine Hoffmann ◽  
Asmus Vogel ◽  
Annette Lolk ◽  
Hanne Gottrup ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Physical Function ◽  
Task Performance ◽  
Dual Task ◽  
Dual Task Performance

Gait assessment in mild cognitive impairment and Alzheimer's disease: The effect of dual-task challenges across the cognitive spectrum

2012 ◽  
Vol 35 (1) ◽  
pp. 96-100 ◽  
Author(s):  
Susan W. Muir ◽  
Mark Speechley ◽  
Jennie Wells ◽  
Michael Borrie ◽  
Karen Gopaul ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Dual Task ◽  
Gait Assessment

Association Between Motor Task Performance and Hippocampal Atrophy Across Cognitively Unimpaired, Amnestic Mild Cognitive Impairment, and Alzheimer’s Disease Individuals

2021 ◽  
pp. 1-7
Author(s):  
Sydney Y. Schaefer ◽  
Michael Malek-Ahmadi ◽  
Andrew Hooyman ◽  
Jace B. King ◽  
Kevin Duff
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Task Performance ◽  
Sex Education ◽  
Low Cost ◽  
Motor Task ◽  
Amnestic Mild Cognitive Impairment ◽  
Hippocampal Atrophy

Hippocampal atrophy is a widely used biomarker for Alzheimer’s disease (AD), but the cost, time, and contraindications associated with magnetic resonance imaging (MRI) limit its use. Recent work has shown that a low-cost upper extremity motor task has potential in identifying AD risk. Fifty-four older adults (15 cognitively unimpaired, 24 amnestic mild cognitive impairment, and 15 AD) completed six motor task trials and a structural MRI. Several measures of motor task performance significantly predicted bilateral hippocampal volume, controlling for age, sex, education, and memory. Thus, this motor task may be an affordable, non-invasive screen for AD risk and progression.

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