Orphanin FQ/nociceptin: an endogenous peptide agonist for the orphan opioid receptor

British Journal of Anaesthesia ◽

10.1093/bja/80.5.577 ◽

1998 ◽

Vol 80 (5) ◽

pp. 577-578 ◽

Author(s):

D G Lambert ◽

D K Grandy

Keyword(s):

Opioid Receptor ◽

Orphanin Fq ◽

Endogenous Peptide ◽

Peptide Agonist

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Functional expression of opioid receptor-like receptor and its endogenous specific agonist nociceptin/orphanin FQ during mouse embryogenesis

Cell Research ◽

10.1038/cr.1997.21 ◽

1997 ◽

Vol 7 (2) ◽

pp. 207-215 ◽

Author(s):

Ya Lan Wu ◽

Guo Huang Fan ◽

Jian Zhao ◽

Yi Zhang ◽

Tian Hua Zhou ◽

...

Keyword(s):

Opioid Receptor ◽

Functional Expression ◽

Orphanin Fq ◽

Mouse Embryogenesis

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The orphan opioid receptor and its endogenous ligand — nociceptin/orphanin FQ

Trends in Pharmacological Sciences ◽

10.1016/s0165-6147(97)90645-3 ◽

1997 ◽

Vol 18 (4) ◽

pp. 293-300 ◽

Author(s):

Graeme Henderson ◽

Alexander T. McKnight

Keyword(s):

Opioid Receptor ◽

Orphanin Fq ◽

Endogenous Ligand

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In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist

Molecular Informatics ◽

10.1002/minf.201500080 ◽

2015 ◽

Vol 35 (1) ◽

pp. 19-24 ◽

Author(s):

Michael Lückmann ◽

Birgitte Holst ◽

Thue W. Schwartz ◽

Thomas M. Frimurer

Keyword(s):

Binding Site ◽

Small Molecule ◽

In Silico ◽

Binding Modes ◽

Neurotensin Receptor ◽

Endogenous Peptide ◽

Neurotensin Receptor 1 ◽

Peptide Agonist

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Cebranopadol: A Novel Potent Analgesic Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.114.213694 ◽

2014 ◽

Vol 349 (3) ◽

pp. 535-548 ◽

Author(s):

Klaus Linz ◽

Thomas Christoph ◽

Thomas M. Tzschentke ◽

Thomas Koch ◽

Klaus Schiene ◽

...

Keyword(s):

Opioid Receptor ◽

Receptor Agonist ◽

Orphanin Fq ◽

Opioid Receptor Agonist

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P.1.c.0511 Heterodimerization of mu opioid receptor and nociceptin/orphanin FQ peptide receptor alters g protein coupling

European Neuropsychopharmacology ◽

10.1016/s0924-977x(09)70411-0 ◽

2009 ◽

Vol 19 ◽

pp. S280-S281

Author(s):

O. Gunduz ◽

E. Baldini ◽

A. Borsodi ◽

S. Benyhe ◽

M. Corbani

Keyword(s):

G Protein ◽

Opioid Receptor ◽

Mu Opioid Receptor ◽

Orphanin Fq ◽

G Protein Coupling ◽

Mu Opioid ◽

Protein Coupling ◽

Peptide Receptor

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Orphan opioid receptor antisense probes block orphanin FQ-induced hyperphagia

European Journal of Pharmacology ◽

10.1016/s0014-2999(98)00272-6 ◽

1998 ◽

Vol 349 (1) ◽

pp. R1-R3 ◽

Author(s):

Liza Leventhal ◽

John P Mathis ◽

Grace C Rossi ◽

Gavril W Pasternak ◽

Richard J Bodnar

Keyword(s):

Opioid Receptor ◽

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Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: Design, synthesis, and structure–activity relationships

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2010.07.034 ◽

2010 ◽

Vol 18 (21) ◽

pp. 7675-7699 ◽

Author(s):

Shigeo Hayashi ◽

Eriko Nakata ◽

Asato Morita ◽

Kunihiko Mizuno ◽

Kenzo Yamamura ◽

...

Keyword(s):

Neuropathic Pain ◽

Orphanin Fq ◽

Design Synthesis ◽

Structure Activity Relationships ◽

Structure Activity ◽

Peptide Agonist

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Erratum to “Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype” [Biochem. Biophys. Res. Commun. 297 (2002) 659–663]

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(02)02479-8 ◽

2002 ◽

Vol 298 (3) ◽

pp. 456

Author(s):

Ying-Xian Pan ◽

Elizabeth Bolan ◽

Gavril W. Pasternak

Keyword(s):

Opioid Receptor ◽

Receptor Subtype ◽

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The Role of Cannabinoid and Opioid Receptor Antagonists in Nociceptin Orphanin FQ Induced Hyperphagia

PsycEXTRA Dataset ◽

10.1037/e413812005-624 ◽

2002 ◽

Author(s):

Thomas A. Pietras ◽

Neil E. Rowland

Keyword(s):

Opioid Receptor ◽

Orphanin Fq ◽

Receptor Antagonists ◽

Opioid Receptor Antagonists

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Orphanin FQ/Nociceptin Potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-Enkephalin–Induced μ-Opioid Receptor Phosphorylation

Molecular Pharmacology ◽

10.1124/mol.105.011536 ◽

2005 ◽

Vol 68 (2) ◽

pp. 447-456 ◽

Author(s):

Hatice Z. Ozsoy ◽

Deepak R. Thakker ◽

Kelly M. Standifer

Keyword(s):

Opioid Receptor ◽

Orphanin Fq ◽

Receptor Phosphorylation ◽

Μ Opioid Receptor

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