scholarly journals Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a

2020 ◽  
Vol 71 (8) ◽  
pp. e215-e217
Author(s):  
Stephanie Popping ◽  
Rosanne Verwijs ◽  
Lize Cuypers ◽  
Mark A Claassen ◽  
Guido E van den Berk ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Antiviral Resistance ◽  
Virus Genotype ◽  
Direct Acting Antiviral ◽  
Genotype 1A ◽  
Sex With Men ◽  
Direct Acting ◽  
Inhibitor Resistance ◽  
Cure Rates

Abstract The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS.

scholarly journals Glecaprevir/Pibrentasvir in patients with hepatitis C virus genotype 1 or 4 and past direct-acting antiviral treatment failure

Hepatology ◽  
2018 ◽  
Vol 67 (4) ◽  
pp. 1253-1260 ◽  
Author(s):  
Fred Poordad ◽  
Stanislas Pol ◽  
Armen Asatryan ◽  
Maria Buti ◽  
David Shaw ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Treatment Failure ◽  
Antiviral Treatment ◽  
Genotype 1 ◽  
Virus Genotype ◽  
Direct Acting Antiviral ◽  
Direct Acting

Sofosbuvir‐based direct acting antiviral therapies for patients with hepatitis C virus genotype 2 infection

2019 ◽  
Vol 34 (9) ◽  
pp. 1620-1625 ◽  
Author(s):  
Chen‐Hua Liu ◽  
Tung‐Hung Su ◽  
Chun‐Jen Liu ◽  
Chun‐Ming Hong ◽  
Hung‐Chih Yang ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Genotype ◽  
Direct Acting Antiviral ◽  
Antiviral Therapies ◽  
Genotype 2 ◽  
Direct Acting
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