scholarly journals P567. Functional outcomes and factors influencing quality of life in patients with ulcerative colitis after total proctocolectomy with ileal pouch anal anastomosis

2016 ◽  
Vol 10 (suppl 1) ◽  
pp. S387.2-S388
2019 ◽  
Vol 14 (6) ◽  
pp. 726-733 ◽  
Author(s):  
Pramodh Chandrasinghe ◽  
Michele Carvello ◽  
Karin Wasmann ◽  
Caterina Foppa ◽  
Pieter Tanis ◽  
...  

Abstract Background The transanal approach to ileal pouch-anal anastomosis [Ta-IPAA] provides better access to the lower pelvis with lower short-term morbidity in ulcerative colitis [UC]. The aim of this study was to assess the long-term functional outcomes after Ta-IPAA vs transabdominal IPAA [Abd-IPAA] in UC. Methods A multicentre cohort analysis was performed between March 2002 and September 2017. Patient characteristics, surgical details and postoperative outcomes were compared. CGQL [Cleveland global quality of life] score at 12 months with a functioning pouch was considered the primary end point. Results A total of 374 patients [100 Ta-IPAA vs 274 Abd-IPAA] were included. Ta-IPAA demonstrated a comparable overall quality of life [CGQL score] to Abd-IPAA [0.75 ± 0.11 vs 0.71 ± 0.14; respectively, p = 0.1]. Quality of life [7.71 ± 1.17 vs 7.30 ± 1.46; p = 0.04] and energy-level items [7.16 ± 1.52 vs 6.66 ± 1.68; p = 0.03] were significantly better after Ta-IPAA, while the quality of health item was comparable [7.68 ± 1.26 vs 7.64 ± 1.44; p = 0.96]. Analysis excluding anastomotic leaks did not change the overall CGQL scores. Stool frequencies [>10/24 h: 22% vs 21%; p = 1.0] and the rate of a single episode of major incontinence during the following 12-month period [27% vs 26%; p = 0.89] were similar. The differences in 30-day morbidity rates [33% vs 41%; p = 0.2] and anastomotic leak rates were not significant [6% vs 13%; p = 0.09]. Conclusions This study provides evidence of comparable long-term functional outcome and quality of life after Ta-IPAA and Abd-IPAA for UC.


Surgery Today ◽  
2017 ◽  
Vol 48 (4) ◽  
pp. 455-461 ◽  
Author(s):  
Kazuhiro Watanabe ◽  
Munenori Nagao ◽  
Hideyuki Suzuki ◽  
Hideaki Karasawa ◽  
Shinobu Ohnuma ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Eren Esen ◽  
Michael J. Grieco ◽  
Arman Erkan ◽  
Erman Aytac ◽  
Alton G. Sutter ◽  
...  

2016 ◽  
Vol 70 (1) ◽  
pp. 38-44
Author(s):  
Marta Kostrejová ◽  
Martin Bortlík ◽  
Dana Ďuricová ◽  
Martin Kolář ◽  
Richard Sequens ◽  
...  

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