scholarly journals DOP058 Does biologic therapy increase the risk for fistula-associated mucinous adenocarcinoma in long standing perianal Crohn's disease?

2017 ◽  
Vol 11 (suppl_1) ◽  
pp. S60-S61
Author(s):  
S. Laureti ◽  
M. Coscia ◽  
L. Gentilini ◽  
P. Gionchetti ◽  
N. Renzi ◽  
...  
2020 ◽  
Vol 158 (6) ◽  
pp. S-728
Author(s):  
Jacqueline Reid ◽  
Colin B. Rumbolt ◽  
Robert A. Mitchell ◽  
Cherry Galorport ◽  
Jacqueline Brown ◽  
...  

2008 ◽  
Vol 74 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Richard Smith ◽  
David Hicks ◽  
Paul I. Tomljanovich ◽  
Shashikant B. Lele ◽  
Ashwani Rajput ◽  
...  

Perianal disease is a common manifestation of Crohn's disease. Rarely malignancy arises in perianal fistulas. The etiology of fistula related cancer remains a subject of debate. We present a unique case of a perianal Crohn's disease with adenomatous epithelialization of a fistula tract and an associated mucinous adenocarcinoma. Our case demonstrates that mucinous adenocarcinoma can arise in long standing perianal Crohn's disease and may be associated with adenomatous transformation of the epithelial lining of the fistula tract.


1991 ◽  
Vol 5 (2) ◽  
pp. 59-61 ◽  
Author(s):  
Wing C Peter Kwan ◽  
Hugh J Freeman

A 47-year-old male with longstanding Crohn’s disease complicated by perianal fistulous disease is described. In this patient, presentation with a large acute ischiorectal abscess resulted in diagnosis of a complicating mucinous adenocarcinoma. Despite the relatively high frequency of perianal complications in Crohn’s disease, diagnosis of carcinoma in this setting is difficult, and survival remains poor.


2012 ◽  
Vol 13 (10) ◽  
pp. 1287-1293 ◽  
Author(s):  
Antonino Spinelli ◽  
Chiara De Cassan ◽  
Matteo Sacchi ◽  
Piero Bazzi ◽  
Silvio Danese ◽  
...  

2015 ◽  
Vol 30 (11) ◽  
pp. 1589-1591 ◽  
Author(s):  
Arianna Zefelippo ◽  
Stefano Costa ◽  
Flavio Caprioli ◽  
Ettore Contessini-Avesani

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